145 Result(s)
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Article
N. Balakrishnan
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Article
Open AccessDrug contraindications in comorbid diseases: a protein interactome perspective
Adverse drug reactions (ADRs) are leading causes of death and drug withdrawals and frequently co-occur with comorbidities. However, systematic studies on the effects of drugs on comorbidities are lacking. Drug...
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Open AccessAuthor Correction: Parkinson’s disease and schizophrenia interactomes contain temporally distinct gene clusters underlying comorbid mechanisms and unique disease processes
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Open AccessParkinson’s disease and schizophrenia interactomes contain temporally distinct gene clusters underlying comorbid mechanisms and unique disease processes
Genome-wide association studies suggest significant overlaps in Parkinson’s disease (PD) and schizophrenia (SZ) risks, but the underlying mechanisms remain elusive. The protein-protein interaction network (‘in...
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Weighted fractional generalized cumulative past entropy and its properties
In this paper, we introduce weighted fractional generalized cumulative past entropy of a nonnegative absolutely continuous random variable. Various properties of the proposed weighted fractional measure are st...
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XAI for intrusion detection system: comparing explanations based on global and local scope
Intrusion Detection System is a device or software in the field of cybersecurity that has become an essential tool in computer networks to provide a secured network environment. Machine Learning based IDS offe...
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On Compatibility/Incompatibility of Two Discrete Probability Distributions in the Presence of Incomplete Specification
Conditional specification of distributions is a develo** area with several applications. In the finite discrete case, a variety of compatible conditions can be derived. In this paper, we revisit a rank–based...
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Fuzzy fault tree reliability analysis based on improved T-S model with application to NC turret
In Takagi and Sugeno (T-S) fuzzy fault tree analysis (FFTA), the construction of T-S fuzzy gates relies too much on expert experience, which will result in inevitable subjective errors. In order to overcome th...
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Preface to a Special Issue in Memory of Professor Theophilos Cacoullos
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Stochastic Comparisons of General Proportional Mean Past Lifetime Frailty Model
In this paper, the general proportional mean past lifetime frailty model is considered, from which the unconditional cumulative distribution and density functions of the lifetime variable are derived. Dependen...
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Non-Parametric Inference for Gini Covariance and its Variants
We obtain simple non-parametric estimators of Gini-based covariance, correlation and regression coefficients. We then establish the consistency and asymptotic normality of the proposed estimators. We provide a...
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Matrix Variate Distribution Theory under Elliptical Models—V: The Non-Central Wishart and Inverted Wishart Distributions
The non-central Wishart and inverted Wishart distributions are studied in this work under elliptical models; some distributional results are based on some generalizations of the well-known Kummer relations, wh...
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Efficient likelihood-based inference for the generalized Pareto distribution
It is well known that inference for the generalized Pareto distribution (GPD) is a difficult problem since the GPD violates the classical regularity conditions in the maximum likelihood method. For parameter e...
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Malware detection and classification using community detection and social network analysis
Despite the efforts of antivirus vendors and researchers to overcome the threat of malware and its growth, malware remains a rampant problem causing significant economic and intellectual property loss. Malware...
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A robust Birnbaum–Saunders regression model based on asymmetric heavy-tailed distributions
Skew-normal/independent distributions provide an attractive class of asymmetric heavy-tailed distributions to the usual symmetric normal distribution. We use this class of distributions here to derive a robust...
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Open AccessGeneralized and social anxiety disorder interactomes show distinctive overlaps with striosome and matrix interactomes
Mechanisms underlying anxiety disorders remain elusive despite the discovery of several associated genes. We constructed the protein–protein interaction networks (interactomes) of six anxiety disorders and not...
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Orderings of the Smallest Claim Amounts from Exponentiated Location-Scale Models
In actuarial science, it is often of interest to compare stochastically extreme claim amounts from heterogeneous portfolios. In this regard, in the present work, we compare the smallest order statistics arisin...
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On a Family of Discrete Log-Symmetric Distributions
The use of continuous probability distributions has been widespread in problems with purely discrete nature. In general, such distributions are not appropriate in this scenario. In this paper, we introduce a c...
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Aero-Engine Health Monitoring with Real Flight Data Using Whale Optimization Algorithm Based Artificial Neural Network Technique
Health monitoring of an aero-engine assumes importance in the light of primary requirements of flight safety and reliability. This paper proposes a novel, simple method for monitoring aircraft engine health us...
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North-east bivariate records
Bivariate records have many application in different fields such as hydrology, economy, finance and weather forecasting; see, for example, the works of Bayramoglu (Metrika 79:725–747, 2016) and Kemalbay and Ba...
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Exact Likelihood-Ratio Tests for a Simple Step-Stress Cumulative Exposure Model with Censored Exponential Data
An accelerated life test (ALT) is commonly used in reliability studies of high quality products. A step-stress experiment is one such ALT that is often used in practice. In this paper, we develop exact inferen...
