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    Article

    Construction of methanol sensing Escherichia coli by the introduction of novel chimeric MxcQZ/OmpR two-component system from Methylobacterium organophilum XX

    Methylobacterium organophilum XX is a type II facultative methylotroph that can grow on methanol. In M. organophilum XX, the MxcQ/MxcE two-component system (TCS) is involved in me...

    Vidhya Selvamani, Murali Kannan Maruthamuthu… in Korean Journal of Chemical Engineering (2017)

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    Article

    Engineering a chimeric malate two-component system by introducing a positive feedback loop in Escherichia coli

    Previous studies constructed a chimeric MalKZ two-component system to sense environmental malate. In this study, we used a positive feedback loop to accelerate and amplify the output signal indicating malate c...

    Irisappan Ganesh, Murali kannan Maruthamuthu… in Korean Journal of Chemical Engineering (2016)

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    Article

    Engineering Escherichia coli to sense acidic amino acids by introduction of a chimeric two-component system

    In an attempt to create an acidic amino acid-sensing Escherichia coli, a chimeric sensor kinase (SK)-based biosensor was constructed using Pseudomonas putida AauS. AauS is a sensor kinase that ultimately controls...

    Sambandam Ravikumar, Irisappan Ganesh… in Korean Journal of Chemical Engineering (2015)