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  1. Article

    Open Access

    Single-cell microRNA-mRNA co-sequencing reveals non-genetic heterogeneity and mechanisms of microRNA regulation

    Measuring multiple omics profiles from the same single cell opens up the opportunity to decode molecular regulation that underlies intercellular heterogeneity in development and disease. Here, we present co-se...

    Nayi Wang, Ji Zheng, Zhuo Chen, Yang Liu, Burak Dura, Minsuk Kwak in Nature Communications (2019)

  2. Article

    Open Access

    Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration

    Following uncontrolled proliferation, a subset of primary tumour cells acquires additional traits/mutations to trigger phenotypic changes that enhance migration and are hypothesized to be the initiators of met...

    Hasini Jayatilaka, Pranay Tyle, Jonathan J. Chen, Minsuk Kwak in Nature Communications (2017)

  3. Article

    Open Access

    A promising biodegradable magnesium alloy suitable for clinical vascular stent application

    We report a Mg alloy Mg-2.2Nd-0.1Zn-0.4Zr (wt.%, denoted as JDBM-2) showing great potential in clinical vascular stent application by integrating the advantages of traditional medical stainless steel and polym...

    Lin Mao, Li shen, Jiahui Chen, **aobo Zhang, Minsuk Kwak, Yu Wu in Scientific Reports (2017)