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  1. Article

    Open Access

    The role of Staphylococcus aureus lipoproteins in hematogenous septic arthritis

    Permanent joint dysfunction is a devastating complication in patients with septic arthritis. Staphylococcus aureus (S. aureus) lipoproteins (Lpp), the predominant ligands for TLR2, are known to be arthritogenic a...

    Majd Mohammad, Zhicheng Hu, Abukar Ali, Pradeep Kumar Kopparapu in Scientific Reports (2020)

  2. Article

    Open Access

    Staphylococcus aureus induces DNA damage in host cell

    Staphylococcus aureus causes serious medical problems in human and animals. Here we show that S. aureus can compromise host genomic integrity as indicated by bacteria-induced histone H2AX phosphorylation, a marke...

    Martine Deplanche, Nassim Mouhali, Minh-Thu Nguyen, Chantal Cauty in Scientific Reports (2019)

  3. Article

    Open Access

    Lipid moieties on lipoproteins of commensal and non-commensal staphylococci induce differential immune responses

    Lipoproteins (Lpp) of Gram-positive bacteria are major players in alerting our immune system. Here, we show that the TLR2 response induced by commensal species Staphylococcus aureus and Staphylococcus epidermidis

    Minh-Thu Nguyen, Julia Uebele, Nimerta Kumari, Hiroshi Nakayama in Nature Communications (2017)