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  1. Article

    Open Access

    Increased incidence and diverse manifestations of multiple evanescent white dot syndrome during the COVID-19 pandemic

    The advent of coronavirus disease 2019 (COVID-19) pandemic has affected the incidence and course of various diseases and numerous studies have investigated ocular involvement associated with COVID-19 and corre...

    Yong Yeon Song, Jung Tae Kim, Young Suk Chang, Min-Woo Lee in Scientific Reports (2024)

  2. Article

    Open Access

    A multimodal machine learning model for predicting dementia conversion in Alzheimer’s disease

    Alzheimer’s disease (AD) accounts for 60–70% of the population with dementia. Mild cognitive impairment (MCI) is a diagnostic entity defined as an intermediate stage between subjective cognitive decline and de...

    Min-Woo Lee, Hye Weon Kim, Yeong Sim Choe, Hyeon Sik Yang, Jiyeon Lee in Scientific Reports (2024)

  3. Article

    Open Access

    Long-term air pollution exposure is associated with higher incidence of ST-elevation myocardial infarction and in-hospital cardiogenic shock

    Previous studies have reported the association between myocardial infarction (MI) and air pollution (AP). However, limited information is available regarding the long-term effects of AP on the relative inciden...

    **ah Cha, Se Yeon Choi, Seung-Woon Rha, Byoung Geol Choi in Scientific Reports (2024)

  4. Article

    Open Access

    Changes in peripapillary microvasculature in patients with type 2 diabetes patients: effect of systemic hypertension

    To determine the effect of hypertension (HTN) on the peripapillary microvasculature in type 2 diabetes mellitus (T2DM) patients without diabetic retinopathy (DR). The patients were classified into three groups...

    Jae-Yun Sung, Kook-Hyung Lee, Ji-Ho Jun, Min-Woo Lee in Scientific Reports (2023)

  5. Article

    Open Access

    Vertical asymmetry analysis of the macular microvasculature in epiretinal membrane patients with open-angle glaucoma

    To identify the usefulness of vertical asymmetry analysis of the retinal microvasculature in epiretinal membrane (ERM) patients accompanied by open-angle glaucoma (OAG). Subjects were divided into three groups...

    Kee-Sup Park, Il Jung, Hyung-Bin Lim, Kook-Hyung Lee, Jung-Tae Kim in Scientific Reports (2023)

  6. Article

    Open Access

    A nationwide study on the current treatment status and natural prognosis of hepatocellular carcinoma in elderly

    The aim of this study was to identify the treatment status and natural prognosis of hepatocellular carcinoma (HCC) patients aged 65 years or older in Korea. We analyzed 3,492 patients’ data from the liver canc...

    Jeong-Ju Yoo, Jayoun Lee, Gi Hong Choi, Min Woo Lee, Dong Ah Park in Scientific Reports (2023)

  7. Article

    Open Access

    A comparison of peripapillary vessel density between subjects with normal-tension glaucoma and primary open-angle glaucoma with similar extents of glaucomatous damage

    The purpose of this study was to identify differences in retinal microvasculature impairments between patients with normal-tension glaucoma (NTG) and those with primary open-angle glaucoma (POAG) with similar ...

    Min-Woo Lee, Hwa-Young Yu, Kee-Sup Park, Sun-Young **, **-Soo Kim in Scientific Reports (2023)

  8. No Access

    Article

    Concurrent self-assembly of RGB microLEDs for next-generation displays

    MicroLED displays have been in the spotlight as the next-generation displays owing to their various advantages, including long lifetime and high brightness compared with organic light-emitting diode (OLED) dis...

    Wonjae Chang, Jungsub Kim, Myoungsoo Kim, Min Woo Lee, Chung Hyun Lim, Gunho Kim in Nature (2023)

  9. Article

    Open Access

    Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation

    Brown adipose tissue (BAT) plays a pivotal role in maintaining body temperature and energy homeostasis. BAT dysfunction is associated with impaired metabolic health. Here, we show that Ssu72 phosphatase is ess...

    Eun-Ji Park, Hyun-Soo Kim, Do-Hyoung Lee, Su-Min Kim in Nature Communications (2023)

  10. Article

    Open Access

    Impact of high myopia on inner retinal layer thickness in type 2 diabetes patients

    To investigate the impact of the combination of type 2 diabetes (DM) and high myopia on inner retinal layer thickness of the macular area. The patients were divided into four groups: control (group 1), patient...

    Jung-Tae Kim, Yong-** Na, Sung-Chul Lee, Min-Woo Lee in Scientific Reports (2023)

  11. Article

    Open Access

    Different characteristics of retinal damage between chronic hypertension and hypertensive retinopathy

    The purpose of this study was to identify how chronic hypertension (HTN) and hypertensive retinopathy (HTNR) have different effects on retinal damage including inner retinal thinning and microvasculature impai...

    Ki-Yup Nam, Min-Woo Lee, Ji-Ho Jun, Jae-Yun Sung, Jung-Yeul Kim in Scientific Reports (2022)

  12. Article

    Open Access

    Effect of Weiss ring on peripapillary retinal nerve fiber layer thickness measurements using SD-OCT

    Spectral-domain optical coherence tomography (SD-OCT) must accurately identify and measure the peripapillary retinal nerve fiber layer (pRNFL) thickness to improve the repeatability and reproducibility, and re...

    Min-Su Kim, Ki-Yup Nam, Young Hoon Hwang, Min-Woo Lee, Woo-Hyuk Lee in Scientific Reports (2022)

  13. Article

    Open Access

    Peripapillary RNFL/vessel density ratio in patients with type2 diabetes without clinical diabetic retinopathy

    To identify how diabetic retinal neurodegeneration (DRN) and microvascular impairment are affected differently by various factors in type 2 diabetes (T2DM) patients without diabetic retinopathy via the ratio o...

    Min-Woo Lee, Jong-Wook Lee, Kook-Hyung Lee, Young-Hoon Lee in Scientific Reports (2022)

  14. Article

    Open Access

    Comparison of retinal layer thickness and microvasculature changes in patients with diabetic retinopathy treated with intravitreous bevacizumab vs panretinal photocoagulation

    To compare changes in retinal layers and microvasculature in diabetic retinopathy (DR) patients after bevacizumab therapy and panretinal photocoagulation (PRP). This prospective study divided patients into two...

    Min-Woo Lee, Seung-Kook Baek, Kook-Hyung Lee, Sung-Chul Lee in Scientific Reports (2022)

  15. Article

    Open Access

    Long-term repeatability of peripapillary optical coherence tomography angiography measurements in healthy eyes

    This is a prospective observational study to establish the short- and long-term repeatability of measurements of peripapillary optical coherence tomography angiography (OCTA) parameters in healthy eyes and ide...

    Woo Hyuk Lee, Min-Woo Lee, Min-Su Kim, Cheon Kuk Ryu, Jung-Yeul Kim in Scientific Reports (2021)

  16. Article

    Open Access

    Changes in each retinal layer and ellipsoid zone recovery after full-thickness macular hole surgery

    To analyze the changes in each retinal layer and the recovery of the ellipsoid zone (EZ) after full-thickness macular hole (FTMH) surgery. Patients who underwent surgery for FTMH were included. Spectral-domain...

    Min-Woo Lee, Tae-Yeon Kim, Yong-Yeon Song, Seung-Kook Baek in Scientific Reports (2021)

  17. Article

    Open Access

    Effects of prolonged type 2 diabetes on changes in peripapillary retinal nerve fiber layer thickness in diabetic eyes without clinical diabetic retinopathy

    To identify the effects of prolonged type 2 diabetes (T2DM) on changes in peripapillary retinal nerve fiber layer (pRNFL) thickness in patients without clinical diabetic retinopathy. Subjects were divided into...

    Min-Woo Lee, Hyung-Bin Lim, Min-Su Kim, Gi-Seok Park, Ki-Yup Nam in Scientific Reports (2021)

  18. Article

    Open Access

    Development of a species-specific transformation system using the novel endogenous promoter calreticulin from oleaginous microalgae Ettlia sp.

    Microalgae not only serve as raw materials for biofuel but also have uses in the food, pharmaceutical, and cosmetic industries. However, regulated gene expression in microalgae has only been achieved in a few ...

    Jun-Woo Lee, Min-Woo Lee, Ji-San Ha, Dae-Soo Kim, EonSeon ** in Scientific Reports (2020)

  19. Article

    Open Access

    Detection of Hepatocellular Carcinoma in Contrast-Enhanced Magnetic Resonance Imaging Using Deep Learning Classifier: A Multi-Center Retrospective Study

    Hepatocellular carcinoma (HCC) is one of the most common malignant tumors and a leading cause of cancer-related death worldwide. We propose a fully automated deep learning model to detect HCC using hepatobilia...

    Junmo Kim, Ji Hye Min, Seon Kyoung Kim, Soo-Yong Shin, Min Woo Lee in Scientific Reports (2020)

  20. Article

    Open Access

    Flexible endoscopic micro-optical coherence tomography for three-dimensional imaging of the arterial microstructure

    Micro-optical coherence tomography (µOCT) is a novel imaging approach enabling visualization of the microstructures of biological tissues at a cellular or sub-cellular level. However, it has been challenging t...

    Junyoung Kim, Sunwon Kim, Joon Woo Song, Hyun Jung Kim, Min Woo Lee in Scientific Reports (2020)

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