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    Article

    Anti-apoptotic Splicing Variant of AIMP2 Recover Mutant SOD1-Induced Neuronal Cell Death

    Although a couple of studies have reported that mutant superoxide dismutase 1 (SOD1), one of the causative genes of familial amyotrophic lateral, interacts physically with lysyl-tRNA synthetase (KARS1) by a ga...

    Myung Geun Kook, Mi Ran Byun, Soo Min Lee, Min Hak Lee in Molecular Neurobiology (2023)

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    Open Access

    Non-Invasive Photodynamic Therapy against -Periodontitis-causing Bacteria

    Periodontitis is initiated by causative bacteria in the gingival sulcus. However, as the lesion is often deep and out of circulation system and biofilm is frequently formed on the bacteria cluster, use of anti...

    Danbi Park, Eun Joo Choi, Kwon-Yeon Weon, Wan Lee, Seoung Hoon Lee in Scientific Reports (2019)

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    Open Access

    TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expression

    Insulin regulates blood glucose levels by binding its receptor and stimulating downstream proteins through the insulin receptor substrate (IRS). Impaired insulin signalling leads to metabolic syndrome, but the...

    Jun-Ha Hwang, A Rum Kim, Kyung Min Kim, Jung Il Park, Ho Taek Oh in Nature Communications (2019)

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    Open Access

    Nanotopological plate stimulates osteogenic differentiation through TAZ activation

    The topographical environment, which mimics the stem cell niche, provides mechanical cues to regulate the differentiation of mesenchymal stem cells (MSC). Diverse topographical variations have been engineered ...

    Jun-Ha Hwang, Dong-Hyun Lee, Mi Ran Byun, A. Rum Kim, Kyung Min Kim in Scientific Reports (2017)