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  1. No Access

    Article

    Differences in directives to limit treatment and discontinue mechanical ventilation between elderly and very elderly patients: a substudy of a multinational observational study

    The aim of this study was to characterize differences in directives to limit treatments and discontinue invasive mechanical ventilation (IMV) in elderly (65–80 years) and very elderly (> 80 years) intensive ca...

    Karen E. A. Burns, Deborah J. Cook, Keying Xu, Peter Dodek… in Intensive Care Medicine (2023)

  2. Article

    Open Access

    Microbial dysbiosis and mortality during mechanical ventilation: a prospective observational study

    Host-associated microbial communities have important roles in tissue homeostasis and overall health. Severe perturbations can occur within these microbial communities during critical illness due to underlying ...

    Daphnée Lamarche, Jennie Johnstone, Nicole Zytaruk, France Clarke… in RESPIRATORY RESEARCH (2018)

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  3. No Access

    Article

    Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock

    Guidelines for shock recommend mean arterial pressure (MAP) targets for vasopressor therapy of at least 65 mmHg and, until recently, suggested that patients with underlying chronic hypertension and atheroscler...

    François Lamontagne, Andrew G. Day, Maureen O. Meade… in Intensive Care Medicine (2018)

  4. No Access

    Article

    Higher versus lower blood pressure targets for vasopressor therapy in shock: a multicentre pilot randomized controlled trial

    In shock, hypotension may contribute to inadequate oxygen delivery, organ failure and death. We conducted the Optimal Vasopressor Titration (OVATION) pilot trial to inform the design of a larger trial examinin...

    François Lamontagne, Maureen O. Meade, Paul C. Hébert… in Intensive Care Medicine (2016)

  5. Article

    Neuroanesthesia and Intensive Care A meta-analysis of noninvasive weaning to facilitate liberation from mechanical ventilation

    To summarize the evidence comparing noninvasive positive pressure ventilation (NPPV) and invasive positive pressure ventilation (IPPV) weaning on mortality, ventilator associated pneumonia and the total durati...

    Karen E.A.Burns, Neill K.J Adhikari, Maureen O Meade in Canadian Journal of Anesthesia (2006)

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  6. Article

    In collaboration with the Canadian Critical Care Society, the Canadian Journal of Anesthesia is proud to publish the best posters presented at the Toronto Critical Care Medicine Symposium 2003 (Adult and Pediatric) held in Toronto, Ontario, October 30 – November 1, 2003

    Conan McCaul, Patrick McNamara, Doreen Engelberts… in Canadian Journal of Anesthesia (2004)

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  7. No Access

    Article

    High values of the pulmonary artery wedge pressure in patients with acute lung injury and acute respiratory distress syndrome

    Objective. To determine the incidence and severity of pulmonary artery wedge pressure (PAWP) elevation in patients with ALI/ARDS. In addition, to examine the effects of clinical variables on the ...

    Niall D. Ferguson, Maureen O. Meade, David C. Hallett… in Intensive Care Medicine (2002)