9 Result(s)

Article

Population-based prevalence and mutational landscape of von Willebrand disease using large-scale genetic databases

Von Willebrand disease (VWD) is a common bleeding disorder caused by mutations in the von Willebrand factor gene (VWF). The true global prevalence of VWD has not been accurately established. We estimated the worl...

Omid Seidizadeh, Andrea Cairo, Luciano Baronciani, Luca Valenti… in npj Genomic Medicine (2023)

Article

Correction to: Usefulness of Fibrosis-4 (FIB-4) score and metabolic alterations in the prediction of SARS-CoV-2 severity

Rosa Lombardi, Vincenzo La Mura, Annalisa Cespiati… in Internal and Emergency Medicine (2022)

Article

Usefulness of fibrosis-4 (FIB-4) score and metabolic alterations in the prediction of SARS-CoV-2 severity

Despite vaccination programs, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remains a public health problem. Identifying key prognostic determinants of severity of the disease may help...

Rosa Lombardi, Vincenzo La Mura, Annalisa Cespiati… in Internal and Emergency Medicine (2022)

Article

Metabolic and genetic determinants for progression to severe liver disease in subjects with obesity from the UK Biobank

Obesity is among the main determinants of nonalcoholic fatty liver disease progression towards severe liver disease (SLD). However, risk factors for SLD in individuals with obesity have not been examined.

Antonio De Vincentis, Federica Tavaglione… in International Journal of Obesity (2022)

Article

The A736V TMPRSS6 polymorphism influences hepcidin and iron metabolism in chronic hemodialysis patients: TMPRSS6 and hepcidin in hemodialysis

Aim of this study was to evaluate whether the A736V TMPRSS6 polymorphism, a major genetic determinant of iron metabolism in healthy subjects, influences serum levels of hepcidin, the hormone regulating iron me...

Serena Pelusi, Domenico Girelli, Raffaela Rametta, Natascia Campostrini… in BMC Nephrology (2013)

Article

The i148m Pnpla3 polymorphism influences serum adiponectin in patients with fatty liver and healthy controls

Reduced adiponectin is implicated in the pathogenesis of nonalcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH), and the I148M Patatin-like phospholipase domain-containing 3 (PNPLA3) polymorphism pre...

Luca Valenti, Raffaela Rametta, Massimiliano Ruscica… in BMC Gastroenterology (2012)

Article

Lack of association between peroxisome proliferator-activated receptors alpha and gamma2 polymorphisms and progressive liver damage in patients with non-alcoholic fatty liver disease: a case control study

Peroxisome proliferator-activated receptors (PPARs) play key roles in the pathogenesis of nonalcoholic fatty liver disease (NAFLD).

Paola Dongiovanni, Raffaela Rametta, Anna Ludovica Fracanzani… in BMC Gastroenterology (2010)