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  1. Article

    Open Access

    Gene signatures of circulating breast cancer cell models are a source of novel molecular determinants of metastasis and improve circulating tumor cell detection in patients

    Progression to stage IV disease remains the main cause of breast cancer-related deaths. Increasing knowledge on the hematogenous phase of metastasis is key for exploiting the entire window of opportunity to in...

    Emanuela Fina, Loredana Cleris, Matteo Dugo… in Journal of Experimental & Clinical Cancer … (2022)

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    Article

    Induction of death receptor 5 expression in tumor vasculature by perifosine restores the vascular disruption activity of TRAIL-expressing CD34+ cells

    The proapoptotic death receptor 5 (DR5) expressed by tumor associated endothelial cells (TECs) mediates vascular disrupting effects of human CD34+ cells engineered to express membrane-bound tumor necrosis factor-...

    Arianna Giacomini, Marco Righi, Loredana Cleris, Silvia L. Locatelli… in Angiogenesis (2013)