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Article

Kindlin-2 modulates MafA and β-catenin expression to regulate β-cell function and mass in mice

β-Cell dysfunction and reduction in β-cell mass are hallmark events of diabetes mellitus. Here we show that β-cells express abundant Kindlin-2 and deleting its expression causes severe diabetes-like phenotypes...

Ke Zhu, Yumei Lai, Huiling Cao, **aochun Bai, Chuanju Liu… in Nature Communications (2020)