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Article
Open AccessDysregulated dendritic cells in sepsis: functional impairment and regulated cell death
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Studies have indicated that immune dysfunction plays a central role in the pathogenesis of sepsis. D...
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Article
Open AccessNLRP4E regulates actin cap formation through SRC and CDC42 during oocyte meiosis
Members of the nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing (NLRP) family regulate various physiological and pathological processes. However, none have been shown ...
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Article
Open AccessQuantitative sequencing using BID-seq uncovers abundant pseudouridines in mammalian mRNA at base resolution
Functional characterization of pseudouridine (Ψ) in mammalian mRNA has been hampered by the lack of a quantitative method that maps Ψ in the whole transcriptome. We report bisulfite-induced deletion sequencing...
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Article
Open AccessPurification and characterization of neutral protease from Aspergillus oryzae Y1 isolated from naturally fermented broad beans
The strain Y1, with a notably high production of neutral protease, was isolated from naturally fermented broad beans and subsequently identified as Aspergillus oryzae, through the analysis of its morphology chara...
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Article
Open AccessOptimization of medium compositions to improve a novel glycoprotein production by Streptomyces kanasenisi ZX01
Streptomyces kanasenisi ZX01 was found to produce a novel glycoprotein GP-1 previously, which was secreted into medium and had significant activity against tobacco mosaic virus. However, ...
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Article
Gastropulmonary Route of Infection and the Prevalence of Microaspiration in the Elderly Patients with Ventilator-Associated Pneumonia Verified by Molecular Microbiology-GM-PFGE
Gastropulmonary route of infection was considered to be an important mechanism of ventilator-associated pneumonia (VAP). However there is little evidence to support this assumption. Moreover, the prevalence o...