-
Article
Open AccessDigital health literacy and digital engagement for people with severe mental ill health across the course of the COVID-19 pandemic in England
An unprecedented acceleration in digital mental health services happened during the COVID-19 pandemic. However, people with severe mental ill health (SMI) might be at risk of digital exclusion, partly because ...
-
Article
Open AccessDemographic, clinical, and service-use characteristics related to the clinician’s recommendation to transition from child to adult mental health services
The service configuration with distinct child and adolescent mental health services (CAMHS) and adult mental health services (AMHS) may be a barrier to continuity of care. Because of a lack of transition polic...
-
Article
An online Sexual Health and Rehabilitation eClinic (TrueNTH SHAReClinic) for prostate cancer patients: a feasibility study
The primary objective was to determine the feasibility of implementing the TrueNTH SHAReClinic as a pan-Canadian sexual health and rehabilitation intervention for patients treated for localized prostate cancer.
-
Article
Wet Chemical Etching of AlN Single Crystals
Anisotropic chemical etching is an important means for characterizing the polarity and defect density of single crystals. In this letter, we present the results of our studies on the etching of bulk AlN crysta...
-
Article
Aluminum Nitride-Silicon Carbide Alloy Crystals Grown on SiC Substrates by Sublimation
AlN-SiC alloy crystals, with a thickness greater than 500 µm, were grown on 4H- and 6H-SiC substrates from a mixture of AlN and SiC powders by the sublimation-recondensation method at 1860-1990 °C. On-axis SiC...
-
Article
A System Level Analysis of Coastal Ecosystem Responses to Hurricane Impacts
Tropical cyclones are major disturbances for coastal systems. Hurricane Harvey made landfall in Texas, USA, on August 25, 2017 as a category 4 storm. There were two distinct disturbances associated with this s...
-
Article
Open AccessA multicenter phase 1 study of PX-866 in combination with docetaxel in patients with advanced solid tumours
This phase I, dose-finding study determined the safety, maximum tolerated dose (MTD)/recommended phase 2 dose (RP2D), pharmacokinetics, and antitumour activity of PX-866, a phosphatidylinositol 3-kinase inhibi...
-
Article
In Situ Studies of Intercritically Austempered Ductile Iron Using Neutron Diffraction
Intercritically austempered ductile irons hold promise for applications requiring fatigue durability, excellent castability, low production energy requirements, reduced greenhouse gas emissions, and excellent ...
-
Article
Family-based behavioural management of childhood obesity: service evaluation of a group programme run in a community setting in the United Kingdom
A service evaluation of a pilot of a family-based behavioural management group programme for childhood obesity was conducted in a community setting in the United Kingdom. A total of 17 families with children a...
-
Article
Open AccessEvaluation of the XRCC1 gene as a phenotypic modifier in BRCA1/2 mutation carriers. Results from the consortium of investigators of modifiers of BRCA1/BRCA2
Single-nucleotide polymorphisms (SNPs) in genes involved in DNA repair are good candidates to be tested as phenotypic modifiers for carriers of mutations in the high-risk susceptibility genes BRCA1 and BRCA2. The...
-
Article
Open AccessLong-term psychosocial impact of alternative management policies in women with low-grade abnormal cervical cytology referred for colposcopy: a randomised controlled trial
The debate continues regarding the best management for women with low-grade abnormal cervical cytology attending colposcopy. We compared psychosocial outcomes of alternative management policies in these women.
-
Article
Use of dietary supplements in the European Prospective Investigation into Cancer and Nutrition calibration study
Dietary supplement use is increasing, but there are few comparable data on supplement intakes and how they affect the nutrition and health of European consumers. The aim of this study was to describe the use o...
-
Article
Open AccessP04-51 LB. The epitopes of two newly identified broad and potent neutralizing antibodies, PG9 and PG16
-
Article
Open AccessS021-06 OA. Potent and broad neutralizing antibodies from HIV-1 non-clade B infected donor reveal a new HIV-1 vaccine target
-
Article
Nuclear, chemical, and physical characterization of nuclear materials
The goal of nuclear forensics is to establish an unambiguous link between illicitly trafficked nuclear material and its origin. The Los Alamos National Laboratory (LANL) Nuclear Materials Signatures Program ha...
-
Article
Open AccessSwitching to letrozole or exemestane improves hot flushes, mood and quality of life in tamoxifen intolerant women
We report an open-label, prospective, crossover study involving 184 post-menopausal women experiencing hot flushes on adjuvant tamoxifen (T). Six weeks after switching to an AI, the primary end point, hot flus...
-
Article
Open AccessA prospective study of neurofibromatosis type 1 cancer incidence in the UK
Neurofibromatosis type 1 (NF1) is an autosomal dominant condition affecting around one in 3000 live births. The manifestations of this condition are extremely variable, even within families, and genetic counse...
-
Article
Cluster headache due to internal carotid artery dissection
-
Article
Associations between BMI, social strata and the estimated energy content of foods
Many studies have shown that the prevalence of obesity is greater in lower social classes. The reasons for this effect however are unclear. Since there is also a link between education and social class, and an...
-
Article
Cerebral β-amyloid deposition is augmented by the –491AA promoter polymorphism in non-demented elderly individuals bearing the apolipoprotein E ε4 allele
The apolipoprotein E ε4 allele (APOE, gene; apoE, protein) is widely accepted as a risk factor for Alzheimer's disease (AD). Our previous studies found that APOEε4 promotes AD pathogenesis by fostering the ea...
