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Numerical Comparison of Nasal Aerosol Administration Systems for Efficient Nose-to-Brain Drug Delivery

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  1. Article

    Open Access

    Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD

    Nasal saline irrigation is highly recommended in patients following functional endoscopic sinus surgery (FESS) to aid the postoperative recovery. Post-FESS patients have significantly altered anatomy leading t...

    Hana Salati, Narinder Singh, Mehrdad Khamooshi, Sara Vahaji in Pharmaceutical Research (2022)

  2. Article

    Open Access

    Comparison of Sinus Deposition from an Aqueous Nasal Spray and Pressurised MDI in a Post-Endoscopic Sinus Surgery Nasal Replica

    Optimising intranasal distribution and retention of topical therapy is essential for effectively managing patients with chronic rhinosinusitis, including those that have had functional endoscopic sinus surgery...

    Joey Siu, James van Strien, Rosa Campbell, Paul Roberts in Pharmaceutical Research (2022)