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  1. Article

    Open Access

    Deep learning-based prediction of post-pancreaticoduodenectomy pancreatic fistula

    Postoperative pancreatic fistula is a life-threatening complication with an unmet need for accurate prediction. This study was aimed to develop preoperative artificial intelligence-based prediction models. Pat...

    Woohyung Lee, Hyo Jung Park, Hack-** Lee, Ki Byung Song in Scientific Reports (2024)

  2. Article

    Open Access

    The clinical implication of minimally invasive versus open pancreatoduodenectomy for non-pancreatic periampullary cancer: a systematic review and individual patient data meta-analysis

    Most studies on minimally invasive pancreatoduodenectomy (MIPD) combine patients with pancreatic and periampullary cancers even though there is substantial heterogeneity between these tumors. Therefore, this s...

    Bas A. Uijterwijk, Meidai Kasai, Daniel H. L. Lemmers in Langenbeck's Archives of Surgery (2023)

  3. Article

    Open Access

    Integrative modeling of tumor genomes and epigenomes for enhanced cancer diagnosis by cell-free DNA

    Multi-cancer early detection remains a key challenge in cell-free DNA (cfDNA)-based liquid biopsy. Here, we perform cfDNA whole-genome sequencing to generate two test datasets covering 2125 patient samples of ...

    Mingyun Bae, Gyuhee Kim, Tae-Rim Lee, ** Mo Ahn, Hyunwook Park in Nature Communications (2023)

  4. No Access

    Article

    Minimally invasive versus open pancreaticoduodenectomy for distal bile duct cancer: an inverse probability of treatment weighting analysis of outcomes

    Minimally invasive pancreaticoduodenectomy (MIPD) has been extended to periampullary cancers, but the oncologic outcome of MIPD for distal bile duct cancer (DBDC) has not been confirmed yet.

    Woohyung Lee, Ki Byung Song, Sarang Hong, Yejong Park, Bong Jun Kwak in Surgical Endoscopy (2023)

  5. No Access

    Article

    Controversial benefit of 5-fluorouracil/leucovorin-based adjuvant chemotherapy for ampullary cancer: a propensity score-matched analysis

    Although surgery is the primary treatment for ampullary cancer (AC), the benefit of adjuvant chemotherapy (CTx) has not yet been confirmed.

    Jaecheol Kang, Woohyung Lee, Jaehoon Shin, Yejong Park in Langenbeck's Archives of Surgery (2022)

  6. No Access

    Article

    The impact of preoperative EUS-FNA for distal resectable pancreatic cancer: Is it really effective enough to take risks?

    Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is frequently used for the preoperative histologic diagnosis of pancreatic cancer. However, debate continues regarding the clinical merits of preop...

    **-Seok Park, Jae Hoon Lee, Tae Jun Song, Joune Seup Lee in Surgical Endoscopy (2022)

  7. No Access

    Article

    Effectiveness of early endoscopic ultrasound-guided drainage for postoperative fluid collection

    Postoperative abdominal fluid collections (PAFCs) are a potentially fatal complication of pancreatobiliary surgery. Endoscopic ultrasound (EUS)-guided drainage has recently been shown to be effective in treati...

    Dongwook Oh, Hwaryong Lee, Tae Jun Song, Do Hyun Park, Sung Koo Lee in Surgical Endoscopy (2022)

  8. Article

    Open Access

    Circulating tumour cells as an indicator of early and systemic recurrence after surgical resection in pancreatic ductal adenocarcinoma

    Early recurrence in pancreatic ductal adenocarcinoma (PDAC) is a decisive factor in determining a patient's prognosis. We determined in our current study whether circulating tumour cells (CTCs) exist in the bl...

    Yejong Park, Hye Ryeong Jun, Hwi Wan Choi, Dae Wook Hwang in Scientific Reports (2021)

  9. Article

    Open Access

    Risk prediction for malignant intraductal papillary mucinous neoplasm of the pancreas: logistic regression versus machine learning

    Most models for predicting malignant pancreatic intraductal papillary mucinous neoplasms were developed based on logistic regression (LR) analysis. Our study aimed to develop risk prediction models using machi...

    Jae Seung Kang, Chanhee Lee, Wookyeong Song, Wonho Choo in Scientific Reports (2020)

  10. Article

    Open Access

    Neoadjuvant modified FOLFIRINOX followed by postoperative gemcitabine in borderline resectable pancreatic adenocarcinoma: a Phase 2 study for clinical and biomarker analysis

    Patients with borderline resectable pancreatic cancer (BRPC) have poor prognosis with upfront surgery.

    Changhoon Yoo, Sang Soo Lee, Ki Byung Song, Jae Ho Jeong in British Journal of Cancer (2020)

  11. Article

    Open Access

    The identification of candidate effective combination regimens for pancreatic cancer using the histoculture drug response assay

    The prognosis for patients with pancreatic cancer is extremely poor, as they are resistant to first line chemotherapy. The long-term goal of this study was to identify effective combination chemotherapy for pa...

    Eunsung Jun, Yejong Park, Woohyung Lee, Jaewoo Kwon, Song Lee in Scientific Reports (2020)

  12. No Access

    Article

    Robotic versus laparoscopic distal pancreatectomy for left-sided pancreatic tumors: a single surgeon’s experience of 228 consecutive cases

    Laparoscopic distal pancreatectomy (LDP) has gained popularity for the treatment of left-sided pancreatic tumors. Robotic systems represent the most recent advancement in minimally invasive surgical treatment ...

    Sarang Hong, Ki Byung Song, Ahmad A. Madkhali, Kyungyeon Hwang in Surgical Endoscopy (2020)

  13. No Access

    Article

    Laparoscopic pancreaticoduodenectomy for periampullary tumors: lessons learned from 500 consecutive patients in a single center

    Laparoscopic pancreaticoduodenectomy (LPD) is a feasible option in selected patients. However, its use has not yet been generalized since it is time-consuming, physically demanding, and technically challenging...

    Ki Byung Song, Song Cheol Kim, Woohyung Lee, Dae Wook Hwang in Surgical Endoscopy (2020)

  14. No Access

    Article

    The Effect of Fibrinogen/Thrombin-Coated Collagen Patch (TachoSil®) Application in Pancreaticojejunostomy for Prevention of Pancreatic Fistula After Pancreaticoduodenectomy: A Randomized Clinical Trial

    Fibrin sealants and topical glue have been studied to reduce the incidence of postoperative pancreatic fistulas (POPF) after pancreatico-enteric anastomosis, but a definitive innovation is still needed. We aim...

    Jaewoo Kwon, Sang Hyun Shin, Sukyung Lee, Guisuk Park in World Journal of Surgery (2019)

  15. No Access

    Article

    Laparoscopic versus open pancreaticoduodenectomy for pancreatic neuroendocrine tumors: a single-center experience

    The efficacy and outcomes of laparoscopic resection for pancreatic neuroendocrine tumors (PNETs) are well established; however, specific data regarding the outcomes of laparoscopic pancreaticoduodenectomy (L-P...

    Hanbaro Kim, Ki Byung Song, Dae Wook Hwang, Jae Hoon Lee in Surgical Endoscopy (2019)

  16. No Access

    Article

    The treatment indication and optimal management of fluid collection after laparoscopic distal pancreatectomy

    Recently, laparoscopic distal pancreatectomy (LDP) has become the standard procedure for resection of left-sided pancreatic tumors. Fluid collection (FC) at the resection margin of the pancreatic stump after L...

    Ki Byung Song, Jaewoo Kwon, Young-Joo Lee, Dae Wook Hwang in Surgical Endoscopy (2019)

  17. Article

    Open Access

    Propensity score-matching analysis comparing laparoscopic and open pancreaticoduodenectomy in elderly patients

    There is little evidence on the safety and benefits of laparoscopic pancreaticoduodenectomy (LPD) in elderly patients; therefore, we evaluated the feasibility and efficacy of this procedure by comparing periop...

    Heeji Shin, Ki Byung Song, Young Il Kim, Young-Joo Lee in Scientific Reports (2019)

  18. No Access

    Article

    Clinicopathologic Characteristics and Optimal Surgical Treatment of Duodenal Gastrointestinal Stromal Tumor

    The clinicopathologic characteristics of duodenal gastrointestinal stromal tumor (GIST) were unclear and the optimal surgical procedure for duodenal GIST remains poorly defined. We aimed to analyze clinicopath...

    Seung Jae Lee, Ki Byung Song, Young-Joo Lee in Journal of Gastrointestinal Surgery (2019)

  19. No Access

    Article

    Nab-paclitaxel plus gemcitabine versus FOLFIRINOX as the first-line chemotherapy for patients with metastatic pancreatic cancer: retrospective analysis

    Purpose nab-paclitaxel plus gemcitabine (AG) and FOLFIRINOX have been established as standard first-line treatment in metastatic pancreatic cancer (mPC). We performed retrospective analysis comparing the efficaci...

    Jihoon Kang, Inhwan Hwang, Changhoon Yoo, Kyu-pyo Kim in Investigational New Drugs (2018)

  20. No Access

    Article

    Carbonic anhydrase 9 expression in well-differentiated pancreatic neuroendocrine neoplasms might be associated with aggressive behavior and poor survival

    Well-differentiated pancreatic neuroendocrine neoplasms/tumors (PanNETs) are rare neoplasms with diverse clinical behavior. Biomarker discovery is important for predicting clinical course and prognosis of PanN...

    Joo Young Kim, Sang Hwa Lee, Soyeon An, Sung Joo Kim, You-Na Sung in Virchows Archiv (2018)

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