9 Result(s)
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Article
Kenong **a
Microbial Genetics and Genomics
Plant Genetics and Genomics
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Article
Open AccessNetAct: a computational platform to construct core transcription factor regulatory networks using gene activity
A major question in systems biology is how to identify the core gene regulatory circuit that governs the decision-making of a biological process. Here, we develop a computational platform, named NetAct, for co...
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Open AccessEvaluation of some aspects in supervised cell type identification for single-cell RNA-seq: classifier, feature selection, and reference construction
Cell type identification is one of the most important questions in single-cell RNA sequencing (scRNA-seq) data analysis. With the accumulation of public scRNA-seq data, supervised cell type identification meth...
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Open AccessUncovering co-expression gene network modules regulating fruit acidity in diverse apples
Acidity is a major contributor to fruit quality. Several organic acids are present in apple fruit, but malic acid is predominant and determines fruit acidity. The trait is largely controlled by the Malic acid (Ma
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A co-expression gene network associated with developmental regulation of apple fruit acidity
Apple fruit acidity, which affects the fruit’s overall taste and flavor to a large extent, is primarily determined by the concentration of malic acid. Previous studies demonstrated that the major QTL malic acid (
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Towards an improved apple reference transcriptome using RNA-seq
The reference genome of apple (Malus × domestica) has been available since 2010. Despite being a milestone in apple genomics, the reference genome is difficult to be used as a reference in RNA-seq (RNA sequencin...
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A natural mutation-led truncation in one of the two aluminum-activated malate transporter-like genes at the Ma locus is associated with low fruit acidity in apple
Acidity levels greatly affect the taste and flavor of fruit, and consequently its market value. In mature apple fruit, malic acid is the predominant organic acid. Several studies have confirmed that the major ...
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Fine genetic map** of the Co locus controlling columnar growth habit in apple
Tree architecture is an important, complex and dynamic trait affected by diverse genetic, ontogenetic and environmental factors. ‘Wijcik McIntosh’, a columnar (reduced branching) sport of ‘McIntosh’ and a valu...
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Open AccessA new implementation of high-throughput five-dimensional clone pooling strategy for BAC library screening
A five-dimensional (5-D) clone pooling strategy for screening of bacterial artificial chromosome (BAC) clones with molecular markers utilizing highly-parallel Illumina GoldenGate assays and PCR facilitates hig...
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Open AccessA high-throughput strategy for screening of bacterial artificial chromosome libraries and anchoring of clones on a genetic map constructed with single nucleotide polymorphisms
Current techniques of screening bacterial artificial chromosome (BAC) libraries for molecular markers during the construction of physical maps are slow, laborious and often assign multiple BAC contigs to a sin...
