11,287 Result(s)

Article

Improved prevention and treatment strategies for differentiation syndrome contribute to reducing early mortality in patients with acute promyelocytic leukemia

Qian Wu, **aofei Yang, **gren Zhang, Mengxing Xue, Xueqing Dou… in Blood Cancer Journal (2024)

Article

Correction: A positive feedback inhibition of isocitrate dehydrogenase 3β on paired-box gene 6 promotes Alzheimer-like pathology

**n Wang, Qian Liu, Hai-tao Yu, Jia-zhao **e… in Signal Transduction and Targeted Therapy (2024)

Article

CD147 TagSNP is associated with the vulnerability to lung cancer in the Chinese population: a case–control study

Lung cancer, with its high morbidity and mortality, presents a major significant public health challenge. CD147, linked to cancer progression and metastasis, is a promising therapeutic target, including for lu...

Yuning **e, Chu Huang, **anlei Zhou, Hongjiao Wu, Ang Li, Xuemei Zhang in Discover Oncology (2024)

Article

Map** alternative splicing events in colorectal cancer

Although aberrant splicing events of genes are closely related to the development and progression of colorectal cancer (CRC), the map** of abnormal splicing events, especially alternative splicing (AS) event...

Yifeng Zheng, Guoqiang Zhong, Qiuyu Song, Haonan Zhang, Shan** Wang… in Discover Oncology (2024)

Article

Deep learning model based on endoscopic images predicting treatment response in locally advanced rectal cancer undergo neoadjuvant chemoradiotherapy: a multicenter study

Neoadjuvant chemoradiotherapy has been the standard practice for patients with locally advanced rectal cancer. However, the treatment response varies greatly among individuals, how to select the optimal candid...

Junhao Zhang, Ruiqing Liu, Xujian Wang… in Journal of Cancer Research and Clinical On… (2024)

Article

Carbon-ion radiotherapy alone vs. standard dose photon radiation with carbon-ion radiotherapy boost for high-grade gliomas: a retrospective study

This study aimed to compare the survival outcome and side effects in patients with primary high-grade glioma (HGG) who received carbon ion radiotherapy (CIRT) alone or as a boost strategy after photon radiatio...

**aoJun Li, YanShan Zhang, YanCheng Ye, SuQing Tian, TingChao Hu, HongYu Chai… in BMC Cancer (2024)

Article

Targeting CD73 limits tumor progression and enhances anti-tumor activity of anti-PD-1 therapy in intrahepatic cholangiocarcinoma

Patients with intrahepatic cholangiocarcinoma (iCCA) respond poorly to immune checkpoint blockades (ICBs). In this study, we aimed to dissect the potential mechanisms underlying poor response to ICBs and explo...

Bao-Ye Sun, Dai Zhang, Wei Gan, **g-Fang Wu… in Journal of Cancer Research and Clinical On… (2024)

Article

Investigating distinct clinical features and constructing a nomogram model for survival probability in adults with cerebellar high-grade gliomas

The clinical features of cerebellar high-grade gliomas (cHGGs) in adults have not been thoroughly explored. This large-scale, population-based study aimed to comprehensively outline these traits and construct ...

Tao Chang, Rui Zhang, Jiahao Gan, Yuan Yang, Yanhui Liu, Yan Ju, **aodong Niu… in BMC Cancer (2024)

Article

LncRNA ZFAS1 regulates ATIC transcription and promotes the proliferation and migration of hepatocellular carcinoma through the PI3K/AKT signaling pathway

Long noncoding RNAs (lncRNAs) exert a significant influence on various cancer-related processes through their intricate interactions with RNAs. Among these, lncRNA ZFAS1 has been implicated in oncogenic roles ...

Baoyang Luo, Lin Zhuang, Ju Huang… in Journal of Cancer Research and Clinical On… (2024)

Article

Nomogram for predicting the probability of rectal anastomotic re-leakage after stoma closure: a retrospective study

In this study, we aimed to identify the risk factors in patients with rectal anastomotic re-leakage and develop a prediction model to predict the probability of rectal anastomotic re-leakage after stoma closure.

Yuegang Li, Gang Hu, **zhu Zhang, Wenlong Qiu, Shiwen Mei, **shan Wang… in BMC Cancer (2024)

Article

An analysis of the role of GAB2 in pan-cancer from a multidimensional perspective

To explore the role of GAB2 in pan-cancer based on bioinformatics analysis.

Yi Yin, Yong Li, Yaoyang Zhang, Qiucheng Jia, Huiming Tang… in Discover Oncology (2024)

Article

MICAL1 promotes the proliferation in acute myeloid leukemia and is associated with clinical prognosis and immune infiltration

Acute myeloid leukemia (AML) is one of the most common hematopoietic malignancies that has a poor prognosis and a high rate of relapse. Dysregulated metabolism plays an important role in AML progression. This ...

Yinsen Song, Zhenzhen Yang, Na Gao, Bojun Zhang in Discover Oncology (2024)

Article

An 18-gene signature of recurrence-associated endothelial cells predicts tumor progression and castration resistance in prostate cancer

The prognostic and therapeutic implications of endothelial cells (ECs) heterogeneity in prostate cancer (PCa) are poorly understood.

Bing-Biao Lin, Qingqing Huang, Binyuan Yan, Mingcheng Liu… in British Journal of Cancer (2024)

Article

eHSP90α in front-line therapy in EGFR exon 19 deletion and 21 Leu858Arg mutations in advanced lung adenocarcinoma

Extracellular heat shock protein 90 AA1(eHSP90α) is intricately linked to tumor progression and prognosis. This study aimed to investigate the difference in the value of eHSP90α in post-treatment response asse...

Yingzhen Bian, Haizhou Liu, **glei Huang, Zhaorong Feng, Yanyan Lin… in BMC Cancer (2024)

Article

Correction: A CT based radiomics analysis to predict the CN0 status of thyroid papillary carcinoma: a two- center study

Zongbao Li, Yifan Zhong, Yan Lv, Jianzhong Zheng, Yu Hu, Yanyan Yang… in Cancer Imaging (2024)

Article

Correction: Apatinib combined with temozolomide in diffuse midline glioma: a novel and effective therapy

Yu-An Li, Chuan Zhao, **g-**g Ge, Cheng Li, Feng-Jun Xue, Shao-Pei Qi… in BMC Cancer (2024)

Article

Impact of baseline body composition on prognostic outcomes in urological malignancies treated with immunotherapy: a pooled analysis of 10 retrospective studies

Numerous epidemiological investigations have explored the impact of body composition on the effectiveness of immune checkpoint inhibitors (ICIs) in urological malignancies (UM) patients, yielding conflicting f...

Wangbin Ma, Qiao Shi, Lilong Zhang, Zhendong Qiu, Tianrui Kuang… in BMC Cancer (2024)

Article

N⁶-methyladenosine modification of circMARK2 enhances cytoplasmic export and stabilizes LIN28B, contributing to the progression of Wilms tumor

The potential involvement of circular RNAs (circRNAs) and N⁶-methyladenosine (m⁶A) modification in the progression of Wilms tumor (WT) has not been fully elucidated. This study investigates the regulatory mechani...

Guannan Shu, Zhang Zhao, Tianxin Zhao… in Journal of Experimental & Clinical Cancer … (2024)

Article

ESRP1-mediated biogenesis of circPTPN12 inhibits hepatocellular carcinoma progression by PDLIM2/ NF-κB pathway

Emerging evidence indicates the pivotal involvement of circular RNAs (circRNAs) in cancer initiation and progression. Understanding the functions and underlying mechanisms of circRNAs in tumor development hold...

Yang Ji, Chuangye Ni, Yanjun Shen, Zhenggang Xu, Lei Tang, Fei Yu… in Molecular Cancer (2024)