6,223 Result(s)

Article

Association of Blood Selenium Levels with Diabetes and Heart Failure in American General Adults: a Cross-sectional Study of NHANES 2011–2020 pre

Selenium is an essential trace element closely related to human health; however, the relationship between blood selenium levels, diabetes, and heart failure remains inconclusive. Therefore, this study aimed to...

Chongyang Zhang, Qingjia Zeng, **nyao Liu, Qile He… in Biological Trace Element Research (2024)

Article

Correction: HDAC1 Promotes Mitochondrial Pathway Apoptosis and Inhibits the Endoplasmic Reticulum Stress Response in High Glucose-Treated Schwann Cells via Decreased U4 Spliceosomal RNA

Tingting **, Ziming Wang, Fan Fan, Wandi Wei, Chenming Zhou… in Neurochemical Research (2024)

Article

FADD regulates adipose inflammation, adipogenesis, and adipocyte survival

Adipose tissue, aside from adipocytes, comprises various abundant immune cells. The accumulation of low-grade chronic inflammation in adipose tissue serves as a primary cause and hallmark of insulin resistance...

Jianlei Tang, Yue Ma, Meilin Li, **angpeng Liu, Yuting Wang… in Cell Death Discovery (2024)

Article

The short peptide encoded by long non-coding RNA RNF217-AS1 inhibits stomach cancer tumorigenesis, macrophage recruitment, and pro-inflammatory responses

Certain long non-coding RNAs (lncRNAs) have potential peptide-coding abilities. Here, the role and molecular basis of the RNF217-AS1-encoded peptide in stomach cancer (SC) tumorigenesis were explored. Here, ln...

Qi Ma, Fei Ma, Bin Zhang, Yonglei Zhang, Liangqun Peng, **angnan Li in Amino Acids (2024)

Article

HMGB1 as an extracellular pro-inflammatory cytokine: Implications for drug-induced organic damage

Drug-induced organic damage encompasses various intricate mechanisms, wherein HMGB1, a non-histone chromosome-binding protein, assumes a significant role as a pivotal hub gene. The regulatory functions of HMGB...

JianYe Yuan, Lin Guo, JiaTing Ma, HeJian Zhang… in Cell Biology and Toxicology (2024)

Article

IL-4/IL-4R axis signaling drives resistance to immunotherapy by inducing the upregulation of Fcγ receptor IIB in M2 macrophages

In recent years, immunotherapy, particularly PD-1 antibodies, have significantly enhanced the outcome of gastric cancer patients. Despite these advances, some patients do not respond well to treatment, highlig...

Jiayu Zhang, Yu Dong, Shan Yu, Keshu Hu, Lingyun Zhang, Min **ong… in Cell Death & Disease (2024)

Article

The ubiquitin-like protein UBTD1 promotes colorectal cancer progression by stabilizing c-Myc to upregulate glycolysis

Dysfunction of the ubiquitin-proteasome system (UPS) is involved in the pathogenesis of various malignancies including colorectal cancer (CRC). Ubiquitin domain containing 1 (UBTD1), a ubiquitin-like protein, ...

Liqin Zhao, Nuoya Yu, Yujia Zhai, Yanan Yang, Yixuan Wang, Yue Yang… in Cell Death & Disease (2024)

Article

GPR116 alleviates acetaminophen-induced liver injury in mice by inhibiting endoplasmic reticulum stress

Acetaminophen (APAP) overdose is a significant contributor to drug-induced liver injury worldwide. G-protein–coupled receptor 116 (GPR116) is an important homeostatic maintenance molecule in the body, but litt...

Qian **ang, Na Li, Yan Zhang, Ting Wang, Ying Wang… in Cellular and Molecular Life Sciences (2024)

Article

Age-related dysregulation of CXCL9/10 in monocytes is linked to impaired innate immune responses in a mouse model of Staphylococcus aureus osteomyelitis

Age-associated impairments in innate immunity are believed to be a causative factor responsible for severe pathogenesis of Staphylococcus aureus (S. aureus) infection in the bone tissue. However, the basis for ag...

Yihuang Lin, Mankai Yang, Chubin Cheng, Jichang Wu… in Cellular and Molecular Life Sciences (2024)

Article

TRAF6 promotes spinal microglial M1 polarization to aggravate neuropathic pain by activating the c-JUN/NF-kB signaling pathway

The neuropathic pain with complex networks of neuroinflammatory activation severely limits clinical therapeutic research. TNF receptor-associated factor 6 (TRAF6) is associated with multiple inflammatory disea...

Yu Zhao, Tiegang Li, Lichun Zhang, Jun Yang, Feng Zhao… in Cell Biology and Toxicology (2024)

Article

Biological impact and therapeutic implication of tumor-associated macrophages in hepatocellular carcinoma

The tumor microenvironment is a complex space comprised of normal, cancer and immune cells. The macrophages are considered as the most abundant immune cells in tumor microenvironment and their function in tumo...

Deming Li, Ting Zhang, Ye Guo, Cong Bi, Ming Liu, Gang Wang in Cell Death & Disease (2024)

Article

Correction: Methylated lncRNAs suppress apoptosis of gastric cancer stem cells via the lncRNA–miRNA/protein axis

Yuan Ci, Yuan Zhang, **aobo Zhang in Cellular & Molecular Biology Letters (2024)

Article

Lactate modulates zygotic genome activation through H3K18 lactylation rather than H3K27 acetylation

In spite of its essential role in culture media, the precise influence of lactate on early mouse embryonic development remains elusive. Previous studies have implicated lactate accumulation in medium affecting...

Yanhua Zhao, Meiting Zhang, **ngwei Huang… in Cellular and Molecular Life Sciences (2024)

Article

CD74 is a functional MIF receptor on activated CD4⁺ T cells

Next to its classical role in MHC II-mediated antigen presentation, CD74 was identified as a high-affinity receptor for macrophage migration inhibitory factor (MIF), a pleiotropic cytokine and major determinan...

Lin Zhang, Iris Woltering, Mathias Holzner… in Cellular and Molecular Life Sciences (2024)

Article

Dexmedetomidine and argon in combination against ferroptosis through tackling TXNIP-mediated oxidative stress in DCD porcine livers

Graft availability from donation after circulatory death (DCD) is significantly limited by ischaemia reperfusion (IR) injury. Effective strategies to mitigate IR injury in DCD grafts are essential to improve g...

Qian Chen, Jiashi Sun, **angfeng Liu, Zhigang Qin, Jieyu Li… in Cell Death Discovery (2024)

Article

Myofibroblasts derived type V collagen promoting tissue mechanical stress and facilitating metastasis and therapy resistance of lung adenocarcinoma cells

Lung cancer is a leading cause of cancer-related mortality globally, with a dismal 5-year survival rate, particularly for Lung Adenocarcinoma (LUAD). Mechanical changes within the tumor microenvironment, such ...

Guangsheng Zhu, Yanan Wang, Yingjie Wang, Hua Huang, Boshi Li… in Cell Death & Disease (2024)

Article

LINC01133 promotes pancreatic ductal adenocarcinoma epithelial–mesenchymal transition mediated by SPP1 through binding to Arp3

Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with limited treatment methods. Long non-coding RNAs (lncRNAs) have been found involved in tumorigenic and progression. The present study revealed th...

Yefan Yang, Yuxi Gong, Ying Ding, Shuning Sun, Rumeng Bai… in Cell Death & Disease (2024)

Article

Publisher Correction: Restrained Mitf-associated autophagy by Mulberroside A ameliorates osteoclastogenesis and counteracts OVX-Induced osteoporosis in mice

Hong Xue, Zhenhua Feng, Putao Yuan, Li Qiao, Qiliang Lou… in Cell Death Discovery (2024)

Article

Retraction Note: Changes in Blood Pressure is Associated with Bone Loss in US Adults: A Cross-Sectional Study from NHANES 2005–2018

Shixuan Liu, Shaobo Wu, Xueyuan Bao, Jiajia Ji, Yuxing Ye… in Calcified Tissue International (2024)

Article

Correction: lncRNA THAP7-AS1, transcriptionally activated by SP1 and post-transcriptionally stabilized by METTL3-mediated m6A modification, exerts oncogenic properties by improving CUL4B entry into the nucleus

Hai-Ting Liu, Yong-**n Zou, Wen-jie Zhu, Sen-Liu… in Cell Death & Differentiation (2024)