7,168 Result(s)

Article

Improved prevention and treatment strategies for differentiation syndrome contribute to reducing early mortality in patients with acute promyelocytic leukemia

Qian Wu, **aofei Yang, **gren Zhang, Mengxing Xue, Xueqing Dou… in Blood Cancer Journal (2024)

Article

Carbon-ion radiotherapy alone vs. standard dose photon radiation with carbon-ion radiotherapy boost for high-grade gliomas: a retrospective study

This study aimed to compare the survival outcome and side effects in patients with primary high-grade glioma (HGG) who received carbon ion radiotherapy (CIRT) alone or as a boost strategy after photon radiatio...

**aoJun Li, YanShan Zhang, YanCheng Ye, SuQing Tian, TingChao Hu, HongYu Chai… in BMC Cancer (2024)

Article

Investigating distinct clinical features and constructing a nomogram model for survival probability in adults with cerebellar high-grade gliomas

The clinical features of cerebellar high-grade gliomas (cHGGs) in adults have not been thoroughly explored. This large-scale, population-based study aimed to comprehensively outline these traits and construct ...

Tao Chang, Rui Zhang, Jiahao Gan, Yuan Yang, Yanhui Liu, Yan Ju, **aodong Niu… in BMC Cancer (2024)

Article

Nomogram for predicting the probability of rectal anastomotic re-leakage after stoma closure: a retrospective study

In this study, we aimed to identify the risk factors in patients with rectal anastomotic re-leakage and develop a prediction model to predict the probability of rectal anastomotic re-leakage after stoma closure.

Yuegang Li, Gang Hu, **zhu Zhang, Wenlong Qiu, Shiwen Mei, **shan Wang… in BMC Cancer (2024)

Article

An 18-gene signature of recurrence-associated endothelial cells predicts tumor progression and castration resistance in prostate cancer

The prognostic and therapeutic implications of endothelial cells (ECs) heterogeneity in prostate cancer (PCa) are poorly understood.

Bing-Biao Lin, Qingqing Huang, Binyuan Yan, Mingcheng Liu… in British Journal of Cancer (2024)

Article

eHSP90α in front-line therapy in EGFR exon 19 deletion and 21 Leu858Arg mutations in advanced lung adenocarcinoma

Extracellular heat shock protein 90 AA1(eHSP90α) is intricately linked to tumor progression and prognosis. This study aimed to investigate the difference in the value of eHSP90α in post-treatment response asse...

Yingzhen Bian, Haizhou Liu, **glei Huang, Zhaorong Feng, Yanyan Lin… in BMC Cancer (2024)

Article

Correction: Apatinib combined with temozolomide in diffuse midline glioma: a novel and effective therapy

Yu-An Li, Chuan Zhao, **g-**g Ge, Cheng Li, Feng-Jun Xue, Shao-Pei Qi… in BMC Cancer (2024)

Article

Impact of baseline body composition on prognostic outcomes in urological malignancies treated with immunotherapy: a pooled analysis of 10 retrospective studies

Numerous epidemiological investigations have explored the impact of body composition on the effectiveness of immune checkpoint inhibitors (ICIs) in urological malignancies (UM) patients, yielding conflicting f...

Wangbin Ma, Qiao Shi, Lilong Zhang, Zhendong Qiu, Tianrui Kuang… in BMC Cancer (2024)

Article

N⁶-methyladenosine modification of circMARK2 enhances cytoplasmic export and stabilizes LIN28B, contributing to the progression of Wilms tumor

The potential involvement of circular RNAs (circRNAs) and N⁶-methyladenosine (m⁶A) modification in the progression of Wilms tumor (WT) has not been fully elucidated. This study investigates the regulatory mechani...

Guannan Shu, Zhang Zhao, Tianxin Zhao… in Journal of Experimental & Clinical Cancer … (2024)

Article

ESRP1-mediated biogenesis of circPTPN12 inhibits hepatocellular carcinoma progression by PDLIM2/ NF-κB pathway

Emerging evidence indicates the pivotal involvement of circular RNAs (circRNAs) in cancer initiation and progression. Understanding the functions and underlying mechanisms of circRNAs in tumor development hold...

Yang Ji, Chuangye Ni, Yanjun Shen, Zhenggang Xu, Lei Tang, Fei Yu… in Molecular Cancer (2024)

Article

Synthetic CT generation for pelvic cases based on deep learning in multi-center datasets

To investigate the feasibility of synthesizing computed tomography (CT) images from magnetic resonance (MR) images in multi-center datasets using generative adversarial networks (GANs) for rectal cancer MR-onl...

**anan Li, Lecheng Jia, Fengyu Lin, Fan Chai, Tao Liu, Wei Zhang… in Radiation Oncology (2024)

Article

Unbiasedly decoding the tumor microenvironment with single-cell multiomics analysis in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with a poor prognosis and limited therapeutic options. Research on the tumor microenvironment (TME) of PDAC has propelled the developme...

Yifan Fu, **xin Tao, Tao Liu, Yueze Liu, Jiangdong Qiu, Dan Su… in Molecular Cancer (2024)

Article

Recursive partitioning analysis for survival stratification and early imaging prediction of molecular biomarker in glioma patients

Glioma is the most common primary brain tumor with high mortality and disability rates. Recent studies have highlighted the significant prognostic consequences of subty** molecular pathological markers using...

**an **e, Chen Luo, Shuai Wu, Wanyu Qiao, Wei Deng, Lei **, Junfeng Lu… in BMC Cancer (2024)

Article

Selective anti-tumor activity of glutathione-responsive abasic site trap** agent in anaplastic thyroid carcinoma

Anaplastic thyroid carcinoma (ATC) is a rare but highly aggressive thyroid cancer with poor prognosis. Killing cancer cells by inducing DNA damage or blockage of DNA repair is a promising strategy for chemothe...

**yan Chai, Mengxue Su, Ruiguo Zhang, Ning Li, Yuanyuan Jia, Wei Zheng… in BMC Cancer (2024)

Article

Clinical applications of telemedicine services using a regional telemedicine platform for cancer treatment: a cross-sectional study

Telemedicine is beneficial for improving treatment efficiency and reducing medical expenses of cancer patients. This study focuses on cancer patients participating in teleconsultations through a regional telem...

Fangfang Cui, Xu Zhang, **anying He, Dongqing Liu, **ming Shi, Ming Ye… in BMC Cancer (2024)

Article

Exploring the causal association between uric acid and lung cancer in east Asian and European populations: a mendelian randomization study

Lung cancer still ranks first in the mortality rate of cancer. Uric acid is a product of purine metabolism in humans. Its presence in the serum is controversial; some say that its high levels have a protective...

** Lin, Linxiang Zhang, **aohui Tang, Jihuang Wang in BMC Cancer (2024)

Article

Positive feedback loop of c-myc/XTP6/NDH2/NF-κB to promote malignant progression in glioblastoma

Recent studies have highlighted the significant role of the NF-κB signaling pathway in the initiation and progression of cancer. Furthermore, long noncoding RNAs (lncRNAs) have been identified as pivotal regul...

Feng **ao, Hong Zhu, Yun Guo… in Journal of Experimental & Clinical Cancer … (2024)

Article

Differentiation of glioma and solitary brain metastasis: a multi-parameter magnetic resonance imaging study using histogram analysis

Differentiation of glioma and solitary brain metastasis (SBM), which requires biopsy or multi-disciplinary diagnosis, remains sophisticated clinically. Histogram analysis of MR diffusion or molecular imaging h...

Yifei Su, Rui Cheng, **xia Guo, Miaoqi Zhang, Junhao Wang, Hongming Ji… in BMC Cancer (2024)

Article

Tumor cell-intrinsic MELK enhanced CCL2-dependent immunosuppression to exacerbate hepatocarcinogenesis and confer resistance of HCC to radiotherapy

The outcome of hepatocellular carcinoma (HCC) is limited by its complex molecular characteristics and changeable tumor microenvironment (TME). Here we focused on elucidating the functional consequences of Mate...

Bufu Tang, **yu Zhu, Yueli Shi, Yajie Wang, **aojie Zhang, Biao Chen… in Molecular Cancer (2024)