2,515 Result(s)

Article

Abstract of the 68th Meeting (Spring Meeting) 6–9 March 1990, Heidelberg

B. Sakmann, J. Schrader, B. Brenner, H. Murer, J. Boeckh… in Pflügers Archiv (1990)

Article

Long–term protection against SIV–induced disease in macaques vaccinated with a live attenuated HIV–2 vaccine

The aim of this study was to test the ability of a live attenuated human immunodeficiency virus type 2 (HIV–2) vaccine to protect cynomolgus monkeys against superinfection with a pathogenic simian immunodefici...

Per Putkonen, Lilian Walther, Yi-Jun Zhang, Su-Ling Li… in Nature Medicine (1995)

Article

Urologic status of 74 spinal cord injury patients from the 1976 Tangshan earthquake, and managed for over 20 years using the Credé maneuver

Objective: To evaluate the urologic safety of long-term Credé maneuver as bladder management in spinal cord injured patients.

S-M Chang, C-L Hou, D-Q Dong, H Zhang in Spinal Cord (2000)

Article

Estrogen protects against the synergistic toxicity by HIV proteins, methamphetamine and cocaine

Human immunodeficiency virus (HIV) infection continues to increase at alarming rates in drug abusers, especially in women. Drugs of abuse can cause long-lasting damage to the brain and HIV infection frequently...

Jadwiga Turchan, Caroline Anderson, Kurt F Hauser, Qinmiao Sun… in BMC Neuroscience (2001)

Article

Incidence rates and populations at risk for spinal cord injury: A regional study

Study design: A 6 year retrospective study was conducted.

DA Burke, RD Linden, YP Zhang, AC Maiste, CB Shields in Spinal Cord (2001)

Article

Convergence of ipsilateral semicircular canal inputs onto single vestibular nucleus neurons in cats

H. Sato, M. Imagawa, H. Meng, X. Zhang, R. Bai, Y. Uchino in Experimental Brain Research (2002)

Article

Insulin signaling inhibits the 5-HT_2Creceptor in choroid plexus via MAP kinase

G protein-coupled receptors (GPCRs) interact with heterotrimeric GTP-binding proteins (G proteins) to modulate acute changes in intracellular messenger levels and ion channel activity. In contrast, long-term c...

Joyce H Hurley, Shengwen Zhang, Leighan S Bye, Mark S Marshall… in BMC Neuroscience (2003)

Article

Equine estrogens differentially inhibit DNA fragmentation induced by glutamate in neuronal cells by modulation of regulatory proteins involved in programmed cell death

Recent data indicate that excitotoxicity of high levels of neurotransmitter glutamate may be mediated via programmed cell death (apoptosis) and that it can be prevented in HT22 mouse hippocampal cells by vario...

YueMei Zhang, **aoFeng Lu, Bhagu R Bhavnani in BMC Neuroscience (2003)

Article

Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors

Inactivating genes in vivo is an important technique for establishing their function in the adult nervous system. Unfortunately, conventional knockout mice may suffer from several limitations including embryon...

Bushra Y Ahmed, Sridhara Chakravarthy, Ruben Eggers, Wim TJMC Hermens… in BMC Neuroscience (2004)

Article

Correction: Corrigendum: Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

Nat. Med. 10, 48–54 (2004) In Figure 3c, the x-axis label for the second bar from the left was incorrect. The label should read, “Stat-3β”. In Figure 4e (top), the y-axis label was incorrect. The label should ...

Tianhong Wang, Guilian Niu, Marcin Kortylewski, Lyudmila Burdelya… in Nature Medicine (2004)

Article

Erratum: CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation

Nat. Med. 10, 982–986 (2004) Supplementary Video 2 was inadvertently omitted and should have been cited on page 984 together with Supplementary Video 1. Supplementary Video 2 is now provided in supplementary i...

Jill R Crittenden, Wolfgang Bergmeier, Yanyu Zhang, Crystal L Piffath… in Nature Medicine (2004)

Article

Erratum: Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene

Nat. Med. 11, 56–62 (2005) The open square in Fig. 1b refers to results from A549 cells, not from uninfected cells.

W Zhang, H Yang, X Kong, S Mohapatra, H San Juan-Vergara, G Hellermann… in Nature Medicine (2005)

Article

Glutamate-induced apoptosis in primary cortical neurons is inhibited by equine estrogens via down-regulation of caspase-3 and prevention of mitochondrial cytochrome c release

Apoptosis plays a key role in cell death observed in neurodegenerative diseases marked by a progressive loss of neurons as seen in Alzheimer's disease. Although the exact cause of apoptosis is not known, a num...

YueMei Zhang, Bhagu R Bhavnani in BMC Neuroscience (2005)

Article

Reduction of motion artifact in pulse oximetry by smoothed pseudo Wigner-Ville distribution

The pulse oximeter, a medical device capable of measuring blood oxygen saturation (SpO2), has been shown to be a valuable device for monitoring patients in critical conditions. In order to incorporate the tech...

Yong-sheng Yan, Carmen CY Poon… in Journal of NeuroEngineering and Rehabilita… (2005)

Article

A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury

During several months of 2003, a newly identified illness termed severe acute respiratory syndrome (SARS) spread rapidly through the world^1,2,3. A new coronavirus (SARS-CoV) was identified as the SARS pathogen^4,5

Keiji Kuba, Yumiko Imai, Shuan Rao, Hong Gao, Feng Guo, Bin Guan… in Nature Medicine (2005)

Article

Signaling pathways mediating a selective induction of nitric oxide synthase II by tumor necrosis factor alpha in nerve growth factor-responsive cells

Inflammation and oxidative stress play a critical role in neurodegeneration associated with acute and chronic insults of the nervous system. Notably, affected neurons are often responsive to and dependent on t...

Michael S Thomas, WenRu Zhang, Paivi M Jordan… in Journal of Neuroinflammation (2005)

Article

Cerebrospinal fluid may mediate CNS ischemic injury

The central nervous system (CNS) is extremely vulnerable to ischemic injury. The details underlying this susceptibility are not completely understood. Since the CNS is surrounded by cerebrospinal fluid (CSF) t...

Yanming F Wang, Judith K Gwathmey, Guorong Zhang… in Cerebrospinal Fluid Research (2005)

Article

Restoration of immunity in lymphopenic individuals with cancer by vaccination and adoptive T-cell transfer

Immunodeficiency is a barrier to successful vaccination in individuals with cancer and chronic infection. We performed a randomized phase 1/2 study in lymphopenic individuals after high-dose chemotherapy and a...

Aaron P Rapoport, Edward A Stadtmauer, Nicole Aqui, Ashraf Badros… in Nature Medicine (2005)

Article

Fertility following spinal cord injury: a systematic review

Systematic review.

D DeForge, J Blackmer, C Garritty, F Yazdi, V Cronin, N Barrowman, M Fang… in Spinal Cord (2005)

Article

Correction: Corrigendum: ATM regulates target switching to escalating doses of radiation in the intestines

Nat. Med. 11, 484–490 (2005) In Figure 2a, ceramide levels at 8 and 12 h after 16 Gy should have read 102 ± 10 and 118 ± 10 percent of control, respectively, and s.e.m. values for the remaining points should b...

H-J Ch'ang, J G Maj, F Paris, H R **ng, J Zhang, J-P Truman… in Nature Medicine (2006)