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Article
Behavioral and physiological stress responses of barren-ground caribou (Rangifer tarandus groenlandicus) to industrial ice roads
Recent and dramatic declines of barren-ground caribou (Rangifer tarandus groenlandicus) in northern Canada have been associated with the effects of climate change, natural population fluctuations, and human distu...
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Article
Functional consequences of perturbing polyamine metabolism in the malaria parasite, Plasmodium falciparum
Inhibition of polyamine biosynthesis and/or the perturbation of polyamine functionality have been exploited with success against parasitic diseases such as Trypanosoma infections. However, when the classical poly...
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Article
Hypoxia induces the expression of the pro-apoptotic gene BNIP3
It has been shown that oxygen deprivation results in apoptotic cell death, and that hypoxia inducible factor 1 (HIF1) and the tumor suppressor p53 play key roles in this process. However, the molecular mechani...