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    Article

    Behavioral and physiological stress responses of barren-ground caribou (Rangifer tarandus groenlandicus) to industrial ice roads

    Recent and dramatic declines of barren-ground caribou (Rangifer tarandus groenlandicus) in northern Canada have been associated with the effects of climate change, natural population fluctuations, and human distu...

    A. Smith, C. J. Johnson, K. Clark in Polar Biology (2023)

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    Functional consequences of perturbing polyamine metabolism in the malaria parasite, Plasmodium falciparum

    Inhibition of polyamine biosynthesis and/or the perturbation of polyamine functionality have been exploited with success against parasitic diseases such as Trypanosoma infections. However, when the classical poly...

    K. Clark, J. Niemand, S. Reeksting, S. Smit, A. C. van Brummelen in Amino Acids (2010)

  3. Article

    Hypoxia induces the expression of the pro-apoptotic gene BNIP3

    It has been shown that oxygen deprivation results in apoptotic cell death, and that hypoxia inducible factor 1 (HIF1) and the tumor suppressor p53 play key roles in this process. However, the molecular mechani...

    K Guo, G Searfoss, D Krolikowski, M Pagnoni, C Franks in Cell Death & Differentiation (2001)