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The clinical benefit of acute GVHD depends on the age at transplantation in patients with adult T-cell leukemia–lymphoma on behalf of the ATL Working Group of the Japan Society for Transplantation and Cellular Therapy

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  1. Article

    Open Access

    Mechanisms of action and resistance in histone methylation-targeted therapy

    Epigenomes enable the rectification of disordered cancer gene expression, thereby providing new targets for pharmacological interventions. The clinical utility of targeting histone H3 lysine trimethylation (H3...

    Makoto Yamagishi, Yuta Kuze, Seiichiro Kobayashi, Makoto Nakashima… in Nature (2024)

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  2. Article

    Open Access

    Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma

    Subclonal genetic heterogeneity and their diverse gene expression impose serious problems in understanding the behavior of cancers and contemplating therapeutic strategies. Here we develop and utilize a captur...

    Makoto Yamagishi, Miyuki Kubokawa, Yuta Kuze, Ayako Suzuki… in Nature Communications (2021)

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