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    Article

    A Population Pharmacokinetic Model of Valproic Acid in Pediatric Patients with Epilepsy: A Non-Linear Pharmacokinetic Model Based on Protein-Binding Saturation

    Valproic acid (VPA) follows a non-linear pharmacokinetic profile in terms of protein-binding saturation. The total daily dose regarding VPA clearance is a simple power function, which may partially explain the...

    Junjie Ding, Yi Wang, Weiwei Lin, Changlian Wang, Limei Zhao in Clinical Pharmacokinetics (2015)

  2. Article

    Open Access

    Analysis of gastroscopy results among healthy people undergoing a medical checkup: a retrospective study

    The association of upper gastrointestinal endoscopic findings with sex, age, and Helicobacter pylori infection in asymptomatic healthy people is unclear. The aim of this study was to retrospectively determine the...

    Haosu Huang, Yanting Rong, Meng Wang, Zimeng Guo, Yanghua Yu in BMC Gastroenterology (2020)

  3. Article

    Open Access

    Predictors of Mortality and Drug Resistance Among Carbapenem-Resistant Enterobacteriaceae-Infected Pancreatic Necrosis Patients

    Carbapenem-resistant Enterobacteriaceae (CRE) has emerged as a global threat to hospitalization patients. Infected pancreatic necrosis (IPN) leads to high risks of CRE infections with increasing mortality. Our st...

    Di Wu, Jie **ao, Junjie Ding, Yan Jia, Zimeng Guo in Infectious Diseases and Therapy (2021)

  4. Article

    Open Access

    Predictors of mortality in acute pancreatitis complicated with multidrug-resistant Klebsiella pneumoniae infection

    Multidrug-resistant (MDR) Klebsiella pneumoniae infections, from pancreatic infections to bloodstream infections, influence the mortality of patients with acute pancreatitis (AP) on the condition of limited antib...

    Di Wu, Junjie Ding, Yan Jia, Huanmiao Liu, Jie **ao, Jie Peng in BMC Infectious Diseases (2021)

  5. Article

    Open Access

    Factors influencing hospital stay duration for patients with mild ischemic colitis: a retrospective study

    Ischemic colitis is the most prevalent ischemic injury of the gastrointestinal tract. The majority of patients with mild ischemic colitis usually achieve complete clinical recovery shortly. However, the predic...

    Haosu Huang, Hanyue Wang, Zhenpu Long, Meng Wang in European Journal of Medical Research (2022)