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  1. No Access

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    Identification of α-d-glucose-1-phosphate cytidylyltransferase involved in Ebosin biosynthesis of Streptomyces sp. 139

    Ebosin, a novel exopolysaccharide produced by Streptomyces sp. 139 has antagonist activity for IL-1R in vitro and remarkable anti-rheumatic arthritis activity in vivo. Its biosynthesis gene cluster (ste) has been...

    **ao-Qiang Qi, Qing-Li Sun, Li-** Bai… in Applied Microbiology and Biotechnology (2009)

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    Identification of a methyltransferase encoded by gene stel16 and its function in Ebosin biosynthesis of Streptomyces sp. 139

    Streptomyces sp. 139 generates a novel exopolysaccharide (EPS) designated as Ebosin, which exerts an antagonistic effect on IL-1R in vitro and anti-rheumatic arthritis activity in vivo. A ste gene cluster for Ebo...

    Hong-Guan **e, Yong-Gang Bao, Li-** Bai, Jun-Jie Shan… in The Journal of Microbiology (2009)

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    Article

    Knockout of the gene (ste15) encoding a glycosyltransferase and its function in biosynthesis of exopolysaccharide in Streptomyces sp. 139

    Streptomyces sp. 139 produces a novel exopolysaccharide (EPS) designated Ebosin which has antagonistic activity for IL-1R in vitro and remarkable anti-rheumatic arthritis activity in vivo...

    Qing-Li Sun, Ling-Yan Wang, Jun-Jie Shan, Rong Jiang… in Archives of Microbiology (2007)