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    Phospholipase Cγ1 negatively regulates growth hormone signalling by forming a ternary complex with Jak2 and protein tyrosine phosphatase-1B

    Growth hormone binds to its membrane receptor (GHR), whereby it regulates many cellular functions, including proliferation, differentiation and chemotaxis. However, although the activation of growth hormone-me...

    Jang Hyun Choi, Hyeon Soo Kim, Sun-Hee Kim, Yong Ryoul Yang… in Nature Cell Biology (2006)