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  1. Article

    Open Access

    Trivalent soluble TNF Receptor, a potent TNF-α antagonist for the treatment collagen-induced arthritis

    Tumor necrosis factor is a major pro-inflammatory cytokine which triggers various physiological consequences by binding to and trimerizing its receptors, and has been the single most sought-after drug target f...

    **aofang Cui, Linmo Chang, Youwei Li, Qianrui Lv, Fei Wang… in Scientific Reports (2018)

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    Article

    Linear dynamic range for signal detection in fluorescent differential display

    We have determined the linear dynamic range in signal detection by Fluorescent Differential Display (FDD) using conditionally induced mRNA expression of the p53 tumor-suppressor gene as a control. By serial sp...

    Yong-jig Cho, Jonathan D. Meade, Blake R. Shester, Jamie C. Walden… in Biotechnology Letters (2010)

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    Article

    Proof-reading signal accuracy of gene expression by binary differential display

    Differential display (DD) is commonly used for identifying differentially expressed genes. However, each cDNA species identified by DD must be verified so a “real difference” can be differentiated from false p...

    Yong-jig Cho, Jonathan D. Meade, Blake R. Shester, Jamie C. Walden… in Biotechnology Letters (2010)

  4. No Access

    Article

    A protocol for differential display of mRNA expression using either fluorescent or radioactive labeling

    Since its invention in the early 1990s, differential display (DD) has become one of the most commonly used techniques for identifying differentially expressed genes at the mRNA level. Unlike other genomic appr...

    Peng Liang, Jonathan D Meade, Arthur B Pardee in Nature Protocols (2007)