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Article
Suppression of pancreatic cancer cell invasion by a cyclooxygenase-2-specific inhibitor
Pancreatic cancer is characterized by invasive and metastatic potential. In this study, effects of the COX-2 inhibitor JTE-522 on cell viability, invasion, and invasion-related cellular properties were determi...
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Article
Surgical treatment for lung cancer in the left lung complicated by isolated right thoracic isomerism
The term “isolated right thoracic isomerism” is used to describe a situation in which the anatomy of the bronchi, lung lobes, and pulmonary vessels on the left side is similar to that on the right side with no...
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Article
Innate immune therapy with a Bacillus Calmette-Guérin cell wall skeleton after radical surgery for non-small cell lung cancer: A case-control study
We investigated whether adjuvant immunotherapy with Bacillus Calmette-Guérin (BCG) cell wall skeleton (CWS) and surgical resection was better than resection, with or without other adjuvant therapy, for patient...
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Article
Open AccessMalignant pleural mesothelioma with long-term tumor disappearance of a local relapse after surgery: a case report
There have been few reports of spontaneous regression of malignant pleural mesothelioma, but the mechanism for this is unknown. We present a case report on a patient with malignant pleural mesothelioma showing...
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Article
Surgical resection of pulmonary metastases from meningioma: Report of a case
Meningiomas rarely metastasize, and little information on pulmonary metastasectomy from meningioma has been documented. We herein report a case of a potentially curative resection for meningioma that metastasi...
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Article
Surgical treatment for gastrointestinal metastasis of non-small-cell lung cancer after pulmonary resection
Gastrointestinal metastasis is not common in recurrent non-small-cell lung cancer (NSCLC) patients. There is thus limited information on clinical outcome for these patients. This report presents the clinical c...
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Article
Surgical management of primary intrathoracic goiters
Intrathoracic goiters account for 3.1%–5.8% of all mediastinal masses. Primary intrathoracic goiters, which receive their blood supply from mediastinal vessels and disconnect at the cervical thyroid, are even ...
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Article
A possible abscopal effect of post-irradiation immunotherapy in two patients with metastatic lung tumors
As well as its local effects, radiotherapy leads to the delayed regression of distant non-irradiated lesions. These abscopal effects are most likely mediated by the innate immune system. Patient 1, a 74-year-o...
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Article
Open AccessPrimary papillary carcinoma of the thymus with invasion into subcutaneous tissue through the sternum
Thymic carcinoma is a rare malignant neoplasm. We present a Japanese case of papillary carcinoma of thymus in a 64-year-old man that invaded into subcutaneous tissue penetrating the sternum. We describe the cl...
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Article
Prognosis associated with surgery for non-small cell lung cancer and synchronous brain metastasis
Several reports have described extended survival after aggressive surgical treatment for non-small cell lung cancer (NSCLC) and synchronous brain metastasis. This retrospective analysis assesses the prognostic...
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Article
A simple risk scoring system for predicting acute exacerbation of interstitial pneumonia after pulmonary resection in lung cancer patients
Lung cancer patients with interstitial lung diseases (ILDs) who have undergone pulmonary resection often develop acute exacerbation of interstitial pneumonia (AE) in the post-operative period. To predict who i...
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Article
Pulmonary metastasectomy: outcomes and issues according to the type of surgical resection
According to a recent report by the Committee for Scientific Affairs of the Japanese Association for Thoracic Surgery, pulmonary metastasectomy accounted for as many as 10.2 % of all entry cases of general tho...
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Article
Pleural recurrence after surgery for pleomorphic adenoma arising from peripheral lung: computed tomography-guided percutaneous needle biopsy as a possible mechanism of local failure
A 75-year-old male was referred to our hospital because of an abnormal shadow found in the right lung 2 years prior that had been increasing in size. Chest computed tomography showed a 1-cm well-defined nodule...
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Article
Open AccessA phase II trial evaluating the efficacy and safety of perioperative pirfenidone for prevention of acute exacerbation of idiopathic pulmonary fibrosis in lung cancer patients undergoing pulmonary resection: West Japan Oncology Group 6711 L (PEOPLE Study)
Idiopathic pulmonary fibrosis (IPF) often accompanies lung cancer, and life-threatening acute exacerbation (AE) of IPF (AE-IPF) is reported to occur in 20 % of IPF patients who undergo lung cancer surgery. Pir...
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Article
Open AccessPost-operative AICS status in completely resected lung cancer patients with pre-operative AICS abnormalities: predictive significance of disease recurrence
The AminoIndexTM Cancer Screening (AICS) system, a plasma-free amino acid (PFAA)-based multivariate discrimination index, is a blood screening test for lung cancer based on the comparison of PFAA concentrations b...
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Article
Open AccessOutcomes of surgical resection for pulmonary metastasis from ovarian cancer
Due to its rarity, information on pulmonary metastasectomy for pulmonary metastasis from ovarian cancer is limited.
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Article
Open AccessPreoperative AminoIndex Cancer Screening (AICS) abnormalities predict postoperative recurrence in patients undergoing curative resection for non-small cell lung cancer
AminoIndex™ Cancer Screening (AICS (lung)) was developed as a screening test for lung cancer using a multivariate analysis of plasma-free amino acid (PFAA) profiles. According to the developed index composed o...
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Article
Open AccessLong-term survival in thymic carcinoma with postoperative pleural dissemination
We report a patient with thymic squamous cell carcinoma who underwent multiple rounds of surgical resection and definitive radiotherapy for both primary tumor and postoperative recurrence. However, the patient...
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Article
Open AccessSmall-sized type A thymoma with pulmonary metastasis: a case report
Type A thymomas comprise a homogenous population of neoplastic epithelial cells that are characterized by a spindle/oval shape without nuclear atypia. They may be accompanied by few non-neoplastic lymphocytes....
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Article
Surgical indication of pulmonary metastasis arising from osteosarcoma or soft tissue sarcoma
Metastasectomy is often the local treatment for pulmonary metastases arising from osteosarcoma or soft tissue sarcoma. However, there have been few investigations on the outcomes of patients who undergo this p...
