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  1. Article

    Open Access

    Characterization of inositol lipid metabolism in gut-associated Bacteroidetes

    Inositol lipids are ubiquitous in eukaryotes and have finely tuned roles in cellular signalling and membrane homoeostasis. In Bacteria, however, inositol lipid production is relatively rare. Recently, the prom...

    Stacey L. Heaver, Henry H. Le, Peijun Tang, Arnaud Baslé in Nature Microbiology (2022)

  2. Article

    Open Access

    Sphingolipids produced by gut bacteria enter host metabolic pathways impacting ceramide levels

    Gut microbes are linked to host metabolism, but specific mechanisms remain to be uncovered. Ceramides, a type of sphingolipid (SL), have been implicated in the development of a range of metabolic disorders fro...

    Elizabeth L. Johnson, Stacey L. Heaver, Jillian L. Waters in Nature Communications (2020)

  3. Article

    Open Access

    The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health

    The Christensenellaceae, a recently described family in the phylum Firmicutes, is emerging as an important player in human health. The relative abundance of Christensenellaceae in the human gut is inversely relat...

    Jillian L. Waters, Ruth E. Ley in BMC Biology (2019)