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    Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis

    Interleukin-1β (IL-1β), a key pro-inflammatory cytokine, is majorly produced by macrophages through NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome, which has been identified as the culp...

    Cheng Chen, Yong-mei Ren, Jian-zhong Zhu, Jia-li Chen in Acta Pharmacologica Sinica (2022)

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    Berberine remodels adipose tissue to attenuate metabolic disorders by activating sirtuin 3

    Adipose tissue remodelling is considered a critical pathophysiological hallmark of obesity and related metabolic diseases. Berberine (BBR), a natural isoquinoline alkaloid, has potent anti-hyperlipidaemic and ...

    Dan Li, Chao Yang, Jian-zhong Zhu, Eduardo Lopez, Tian Zhang in Acta Pharmacologica Sinica (2022)

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    Electrochemical characteristics of boron-doped polycrystalline diamond film electrodes

    The electrochemical characteristics of boron-doped polycrystalline diamond thin film electrodes with 4×4 mm2 in size have been studied using cyclic voltammetry and a potentiostatic method. The diamond electrode e...

    Jian Zhong Zhu, Shen Zhong Yang, Pei Ling Zhu in Fresenius' Journal of Analytical Chemistry (1995)