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Article
Association between human blood metabolome and the risk of pre-eclampsia
Pre-eclampsia is a complex multi-system pregnancy disorder with limited treatment options. Therefore, we aimed to screen for metabolites that have causal associations with preeclampsia and to predict target-me...
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Article
Open AccessProtection of the marginal mandibular branches of the facial nerves by different surgical procedures in comprehensive cervical lymphadenectomy for locally advanced oral and oropharyngeal cancer: a multicenter experience
According to the different characteristics of patients and cervical lymph node metastasis of oral and oropharyngeal cancer, the marginal mandibular branches of facial nerves were treated by different surgical ...
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Article
Open AccessLoss of FOXC1 contributes to the corneal epithelial fate switch and pathogenesis
Forkhead box C1 (FOXC1) is required for neural crest and ocular development, and mutations in FOXC1 lead to inherited Axenfeld–Rieger syndrome. Here, we find that FOXC1 and paired box 6 (PAX6) are co-expressed in...
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Article
Open AccessRisk factors for bile leakage after primary closure following laparoscopic common bile duct exploration: a retrospective cohort study
Primary closure following laparoscopic common bile duct exploration (LCBDE) has been widely adopted because of the efficacy and safety in treatment of common bile duct (CBD) stones. However, the risk factors f...
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Article
CLU rs2279590 polymorphism contributes to Alzheimer’s disease susceptibility in Caucasian and Asian populations
It is reported that CLU rs2279590 polymorphism is significantly associated with Alzheimer’s disease (AD) in European ancestry. Recent studies investigated rs2279590 polymorphism in Asian population (Chinese, J...
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Article
Breast Ultrasound Image Classification Based on Multiple-Instance Learning
Breast ultrasound (BUS) image segmentation is a very difficult task due to poor image quality and speckle noise. In this paper, local features extracted from roughly segmented regions of interest (ROIs) are us...