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  1. Article

    Open Access

    A gH/gL-encoding replicon vaccine elicits neutralizing antibodies that protect humanized mice against EBV challenge

    Epstein-Barr virus (EBV) is associated with several malignancies, neurodegenerative disorders and is the causative agent of infectious mononucleosis. A vaccine that prevents EBV-driven morbidity and mortality ...

    Kristina R. Edwards, Harman Malhi, Karina Schmidt, Amelia R. Davis in npj Vaccines (2024)

  2. Article

    Open Access

    Accelerated prime-and-trap vaccine regimen in mice using repRNA-based CSP malaria vaccine

    Malaria, caused by Plasmodium parasites, remains one of the most devastating infectious diseases worldwide, despite control efforts to lower morbidity and mortality. Both advanced candidate vaccines, RTS,S and R2...

    Zachary MacMillen, Kiara Hatzakis, Adrian Simpson, Melanie J. Shears in npj Vaccines (2024)

  3. Article

    A chikungunya fever vaccine utilizing an insect-specific virus platform

    New vaccine approaches that safely elicit immunity are needed to protect against infectious disease. Erasmus et al. report their development of an insect-virus-based platform that they use to engineer a protectiv...

    Jesse H Erasmus, Albert J Auguste, Jason T Kaelber, Huanle Luo in Nature Medicine (2017)