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  1. Article

    Open Access

    KDM6B is an androgen regulated gene and plays oncogenic roles by demethylating H3K27me3 at cyclin D1 promoter in prostate cancer

    Lysine (K)-specific demethylase 6B (KDM6B), a stress-inducible H3K27me3 demethylase, plays oncogenic or antitumoral roles in malignant tumors depending on the type of tumor cell. However, how this histone modi...

    Zhi Cao, **aolei Shi, Feng Tian, Yu Fang, Jason Boyang Wu… in Cell Death & Disease (2021)

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    Article

    Loss of MAOA in epithelia inhibits adenocarcinoma development, cell proliferation and cancer stem cells in prostate

    Monoamine oxidase A (MAOA) is a mitochondrial enzyme, which degrades monoamine neurotransmitters and dietary amines and produces H2O2. Recent studies have shown increased MAOA expression in prostate cancer (PCa),...

    Chun-Peng Liao, Tzu-** Lin, Pei-Chuan Li, Lauren A. Geary, Kevin Chen… in Oncogene (2018)