4 Result(s)
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Article
Jan-Paul Gundlach
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Article
Open AccessNF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancer
The emergence of resistance to systemic therapies in pancreatic ductal adenocarcinoma (PDAC) is still a major obstacle in clinical practice. Both, constitutive and inducible NF-κB activity are known as key pla...
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Open AccessPrognostic significance of high mobility group A2 (HMGA2) in pancreatic ductal adenocarcinoma: malignant functions of cytoplasmic HMGA2 expression
HMGA2 has frequently been found in benign as well as malignant tumors and a significant association between HMGA2 overexpression and poor survival in different malignancies was described. In pancreatic ductal ...
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Open AccessLethal thrombosis of the iliac artery caused by Aspergillus fumigatus after liver transplantation: case report and review of the literature
Aspergillus fumigatus infections frequently occur after solid organ transplantation. Yet, a fungal thrombosis after liver transplantation is an exceptional finding.
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Open AccessCytoplasmic TRAIL-R1 is a positive prognostic marker in PDAC
The death receptors TRAIL-R1 and TRAIL-R2 are frequently overexpressed in cancer and there is an emerging evidence for their important role in malignant progression, also in the case of pancreatic ductal adeno...
