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Global burden study of lower respiratory infections linked to low temperatures: an analysis from 1990 to 2019
Low temperature conditions have been linked to a heightened susceptibility to lower respiratory infections (LRIs). Yet, our comprehension of the LRIs’ disease burden due to such conditions remains limited, esp...
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Open AccessPrenatal exposure to concentrated ambient PM2.5 results in spatial memory defects regulated by DNA methylation in male mice offspring
Ambient fine particulate matter (PM2.5) exposures during pregnancy could lead to adverse birth outcomes, including neurobehavioral development defects. However, limited studies explored the effects and potential ...
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Article
Open AccessNegative air ion exposure ameliorates depression-like behaviors induced by chronic mild stress in mice
The presence of negative air ions (NAI) is suggested to be a beneficial factor in improving psychological status and used in treating depression as an alternative approach. However, more biological evidence fr...
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Article
Ambient PM2.5-induced brain injury is associated with the activation of PI3K/AKT/FoxO1 pathway
PM2.5-related neurological and mental diseases, such as cognitive impairment and stroke, tend to cause disability. Six-week-old male C57BL/6 mice were divided into 6 groups and exposed to concentrated PM2.5 or fi...
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A study on the short-term effect of particulate matter pollution on hospital visits for asthma in children in Shanghai, China
Recently, particulate matter pollution has been worsening, which has been affecting the asthma visits in children. In this study, we assessed the short-term effects of PM10 and PM2.5 on asthma visits in children ...
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Open AccessAirborne particulate matter (PM2.5) triggers ocular hypertension and glaucoma through pyroptosis
Particulate matter (PM) is strongly linked to human health and has detrimental effects on the eye. Studies have, however, focused on the ocular surface, with limited research on the impact of PM2.5 on intraocular...
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Open AccessAirborne particulate matter, population mobility and COVID-19: a multi-city study in China
Coronavirus disease 2019 (COVID-19) is an emerging infectious disease, which has caused numerous deaths and health problems worldwide. This study aims to examine the effects of airborne particulate matter (PM)...
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Article
Farnesoid X receptor mediates hepatic steatosis induced by PM2.5
Ambient particulate matter (PM) newly has been regarded as a conceivable hazard for public health. A large number of studies have described that PM, exceptionally PM2.5, is correlated with respiratory, cardiovasc...
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Article
Effects of high-temperature heat wave and ozone on hypertensive rats
This study aimed to investigate the effects of heat waves and ozone on hypertensive rats. Heat wave and ozone pollution were simulated on the Shanghai Meteorological and Environmental Animal Exposure System. E...
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Open AccessThe association between the seasonality of pediatric pandemic influenza virus outbreak and ambient meteorological factors in Shanghai
The number of pediatric patients diagnosed with influenza types A and B is increasing annually, especially in temperate regions such as Shanghai (China). The onset of pandemic influenza viruses might be attrib...
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Article
AMPK activation ameliorates fine particulate matter-induced hepatic injury
Both the epidemiological and animal experimental studies have reported the association between PM2.5 and respiratory, cardiovascular, and metabolic diseases. However, the study linking PM2.5 and hepatic injury is...
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Effect of diurnal temperature range on outpatient visits for common cold in Shanghai, China
To evaluate the correlations between diurnal temperature range (DTR) and the number of outpatient visits for common cold from Jan. 1, 2008, to Dec. 31, 2010, in the Shanghai metro area; we used a distributed l...
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Short-term effect of PM2.5 on pediatric asthma incidence in Shanghai, China
Recent epidemiological studies pointed out that air pollution has a significant impact on pediatric asthma. Shanghai is one of the biggest cities in China, and the short-term effect of atmospheric particulate ...
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Open AccessDevelopmental programming of obesity by maternal exposure to concentrated ambient PM2.5 is maternally transmitted into the third generation in a mouse model
Obesity is an uncontrolled global epidemic and one of the leading global public health challenges. Maternal exposure to ambient fine particulate matter (PM2.5) may adversely program offspring’s adiposity, suggest...
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Effects of extreme temperatures on hospital emergency room visits for respiratory diseases in Bei**g, China
Extreme temperature is closely associated with human health, but limited evidence is available for the effects of extreme temperatures on respiratory diseases in China. The goal of this study is to evaluate th...
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Open AccessExposure to concentrated ambient PM2.5 alters the composition of gut microbiota in a murine model
Exposure to ambient fine particulate matter (PM2.5) correlates with abnormal glucose homeostasis, but the underlying biological mechanism has not been fully understood. The gut microbiota is an emerging crucial p...
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Effects of different cold-air exposure intensities on the risk of cardiovascular disease in healthy and hypertensive rats
Ten-week-old male Wistar rats (systolic blood pressure, 106–116 mmHg; body weight, 300–320 g) and spontaneously hypertensive rats (systolic blood pressure, 160–176 mmHg; body weight, 210.9–244.9 g) were used a...