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Article
Global burden study of lower respiratory infections linked to low temperatures: an analysis from 1990 to 2019
Low temperature conditions have been linked to a heightened susceptibility to lower respiratory infections (LRIs). Yet, our comprehension of the LRIs’ disease burden due to such conditions remains limited, esp...
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Article
Open AccessPrenatal exposure to concentrated ambient PM2.5 results in spatial memory defects regulated by DNA methylation in male mice offspring
Ambient fine particulate matter (PM2.5) exposures during pregnancy could lead to adverse birth outcomes, including neurobehavioral development defects. However, limited studies explored the effects and potential ...
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Article
Open AccessNegative air ion exposure ameliorates depression-like behaviors induced by chronic mild stress in mice
The presence of negative air ions (NAI) is suggested to be a beneficial factor in improving psychological status and used in treating depression as an alternative approach. However, more biological evidence fr...
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Article
Ambient PM2.5-induced brain injury is associated with the activation of PI3K/AKT/FoxO1 pathway
PM2.5-related neurological and mental diseases, such as cognitive impairment and stroke, tend to cause disability. Six-week-old male C57BL/6 mice were divided into 6 groups and exposed to concentrated PM2.5 or fi...
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Article
Farnesoid X receptor mediates hepatic steatosis induced by PM2.5
Ambient particulate matter (PM) newly has been regarded as a conceivable hazard for public health. A large number of studies have described that PM, exceptionally PM2.5, is correlated with respiratory, cardiovasc...
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Article
AMPK activation ameliorates fine particulate matter-induced hepatic injury
Both the epidemiological and animal experimental studies have reported the association between PM2.5 and respiratory, cardiovascular, and metabolic diseases. However, the study linking PM2.5 and hepatic injury is...
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Article
Open AccessThe activation of antioxidant and apoptosis pathways involved in damage of human proximal tubule epithelial cells by PM2.5 exposure
Exposure to airborne fine particulate matter (PM2.5) has been reported to be harmful to the human kidney. However, whether the activation of oxidative stress and cell apoptosis plays key roles in the nephrotoxici...
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Article
Effect of diurnal temperature range on outpatient visits for common cold in Shanghai, China
To evaluate the correlations between diurnal temperature range (DTR) and the number of outpatient visits for common cold from Jan. 1, 2008, to Dec. 31, 2010, in the Shanghai metro area; we used a distributed l...
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Article
Short-term effect of PM2.5 on pediatric asthma incidence in Shanghai, China
Recent epidemiological studies pointed out that air pollution has a significant impact on pediatric asthma. Shanghai is one of the biggest cities in China, and the short-term effect of atmospheric particulate ...
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Article
Effects of extreme temperatures on hospital emergency room visits for respiratory diseases in Bei**g, China
Extreme temperature is closely associated with human health, but limited evidence is available for the effects of extreme temperatures on respiratory diseases in China. The goal of this study is to evaluate th...
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Article
Linking the soil moisture distribution pattern to dynamic processes along slope transects in the Loess Plateau, China
Soil moisture pulses are a prerequisite for other land surface pulses at various spatiotemporal scales in arid and semi-arid areas. The temporal dynamics and profile variability of soil moisture in relation to...