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  1. No Access

    Article

    The cytotoxic action of four ammine/amine platinum(IV) dicarboxylates: a flow cytometric study

    We have used flow cytometry to study the mechanism of cytotoxic action of a series of ammine/amine Pt(IV) dicarboxylates [ammine diacetatodichloro(cyclohexylamine) platinum(IV), JM216; ammine dibutyratodichlor...

    MG Ormerod, RM Orr, CF O'Neill, T Chwalinski, JC Titley… in British Journal of Cancer (1996)

  2. No Access

    Article

    Apoptotic and non-apoptotic cell death induced by cis and trans analogues of a novel ammine(cyclohexylamine)dihydroxodichloroplatinum(IV) complex

    It has been previously demonstrated that cisplatin induces apoptosis in the CH1 human ovarian carcinoma cell line. This study demonstrates that two novel platinum (Pt) analogues JM149 and JM335, which are the ...

    CF O'Neill, MG Ormerod, D Robertson, JC Titley… in British Journal of Cancer (1996)

  3. No Access

    Article

    Measurement of S-phase fraction and ploidy in sequential fine-needle aspirates from primary human breast tumours treated with tamoxifen

    Sequential fine-needle aspirates (FNAs) for cytodiagnosis and flow cytometry were taken from 21 patients with primary breast carcinoma at intervals ranging from 1 to 3 months after the commencement of first-li...

    IN Fernando, JC Titley, TJ Powles, M Dowsett, PA Trott… in British Journal of Cancer (1994)

  4. No Access

    Article

    Proliferative behaviour of an oestrogen sensitive rat mammary tumour: evidence for a paracrine interaction between tumour and stroma

    An oestrogen-sensitive rat mammary tumour (OES HR1) has been grown in normal female rats and in female and male rats supplemented with oestrone. In some rats, after the tumour was established, both exogenous a...

    MG Ormerod, JC Titley, TAD Smith, AL Tombs, S Eccles in British Journal of Cancer (1993)

  5. No Access

    Article

    The phosphocholine and glycerophosphocholine content of an oestrogen-sensitive rat mammary tumour correlates strongly with growth rate

    An oestrogen sensitive rat mammary tumour was grown in two groups of female and one group of male hooded rats. The male group and one of the female groups were supplemented with oestrogen. The tumours grew mos...

    TAD Smith, S Eccles, MG Ormerod, AJ Tombs, JC Titley, MO Leach in British Journal of Cancer (1991)