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WIP1 phosphatase modulates the Hedgehog signaling by enhancing GLI1 function

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  1. Article

    Open Access

    SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells

    Melanoma is one of the most aggressive types of human cancer, characterized by enhanced heterogeneity and resistance to conventional therapy at advanced stages. We and others have previously shown that HEDGEHO...

    R Santini, S Pietrobono, S Pandolfi, V Montagnani, M D'Amico, J Y Penachioni in Oncogene (2014)