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  1. No Access

    Article

    Tracing cancer networks with phosphoproteomics

    A mass-spectrometry approach for identifying downstream events in cancer signaling pathways may help to tailor therapies to individual patients.

    David B Solit, Ingo K Mellinghoff in Nature Biotechnology (2010)

  2. No Access

    Article

    Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy

    Du et al. describe a bead-based method for high-throughput detection of phosphorylated tyrosine kinases and use it to profile 130 human cancer lines. They show that the tyrosine kinase SRC is frequently activated...

    **yan Du, Paula Bernasconi, Karl R Clauser, D R Mani… in Nature Biotechnology (2009)