46 Result(s)

Article

The Three Networks Framework to Deal with Public Health Emergencies in Guangxi, China

To improve the detection and control of infectious diseases in Guangxi, China.

Geng Wen-kui MSc, Zhuo Jia-tong MSc, Liu De-cheng MSc… in Canadian Journal of Public Health (2006)

Article

Efficacy of different protein descriptors in predicting protein functional families

Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a need to comparatively evaluate the effective...

Serene AK Ong, Hong Huang Lin, Yu Zong Chen, Ze Rong Li, Zhiwei Cao in BMC Bioinformatics (2007)

Article

Evaluation of MHC class I peptide binding prediction servers: Applications for vaccine research

Protein antigens and their specific epitopes are formulation targets for epitope-based vaccines. A number of prediction servers are available for identification of peptides that bind major histocompatibility c...

Hong Huang Lin, Surajit Ray, Songsak Tongchusak, Ellis L Reinherz… in BMC Immunology (2008)

Article

Evaluation of MHC-II peptide binding prediction servers: applications for vaccine research

Initiation and regulation of immune responses in humans involves recognition of peptides presented by human leukocyte antigen class II (HLA-II) molecules. These peptides (HLA-II T-cell epitopes) are increasing...

Hong Huang Lin, Guang Lan Zhang, Songsak Tongchusak, Ellis L Reinherz… in BMC Bioinformatics (2008)

Article

Unambiguous molecular detections with multiple genetic approach for the complicated chromosome 22q11 deletion syndrome

Chromosome 22q11 deletion syndrome (22q11DS) causes a developmental disorder during the embryonic stage, usually because of hemizygous deletions. The clinical pictures of patients with 22q11DS vary because of ...

Chen Yang, Cheng-Hung Huang, Mei-Leng Cheong, Kun-Long Hung… in BMC Medical Genetics (2009)

Article

Simultaneous use of traditional Chinese medicine (Si-Ni-Tang) to treat septic shock patients: study protocol for a randomized controlled trial

Even though there are continually upgraded recommendations for managing sepsis, such as "Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock", mortality is stil...

Huang-Chi Chen, Wen-Chi Chen, Kai-Huang Lin, Yung-Hsiang Chen, Lun-Chien Lo… in Trials (2011)

Article

Quantification and recognition of parkinsonian gait from monocular video imaging using kernel-based principal component analysis

The computer-aided identification of specific gait patterns is an important issue in the assessment of Parkinson's disease (PD). In this study, a computer vision-based gait analysis approach is developed to as...

Shih-Wei Chen, Sheng-Huang Lin, Lun-De Liao, Hsin-Yi Lai… in BioMedical Engineering OnLine (2011)

Article

Serum proteomic, peptidomic and metabolomic profiles in myasthenia gravis patients during treatment with Qiangji Jianli Fang

Qiangji Jianli Fang (QJF) has been used for treatment of myasthenia gravis (MG) in China. However, our understanding of the effects of QJF against MG at the molecular level is limited. This study aims to investig...

Chunmei Wang, Yonghai Lu, Zhixi Chen, **aobin Liu, Huangquan Lin… in Chinese Medicine (2012)

Article

Erratum to: Energy Field Simulating of Heat Transfer Capability and Damage Evaluation on an Improved Langmuir Probe

Huangbin Lin, Haiyuan Qiu, Tao Wang in Journal of Fusion Energy (2012)

Article

NF-κB repressing factor downregulates basal expression and mycobacterium tuberculosis induced IP-10 and IL-8 synthesis via interference with NF-κB in monocytes

Our previous study showed NF-κB repressing factor (NKRF) downregulates IP-10 and IL-8 synthesis in the peripheral blood mononuclear cells and alveolar macrophages of TB patients with high bacterial loads. Howe...

Kuo-Hsiung Huang, Chun-Hua Wang, Chien-Huang Lin… in Journal of Biomedical Science (2014)

Article

Indication of nerve growth factor binding components from herbal extracts by HerboChip: a platform for drug screening on a chip

HerboChip is an array of different fractions deriving from herbal extracts. This study aimed to identify effective components from Chinese medicine (CM) that interact with nerve growth factor (NGF) as a target...

Pinky Sum Chi Lee, Laura Minglu Zhang, Artemis Lu Yan… in Chinese Medicine (2016)

Article

A comparative, retrospective, observational study of the clinical and microbiological profiles of post-penetrating keratoplasty keratitis

Infectious keratitis after penetrating keratoplasty (PK) is a devastating condition that may result in graft failure and poor visual outcome. In this study, we retrospectively reviewed the medical records of p...

I-Huang Lin, Yi-Sheng Chang, Sung-Huei Tseng, Yi-Hsun Huang in Scientific Reports (2016)

Article

Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of matrix metalloproteinase-2 through down-regulating miR-376c expression

Thrombospondin-2 (TSP-2) is a secreted matricellular glycoprotein that is found to mediate cell-to-extracellular matrix attachment and participates in many physiological and pathological processes. The express...

Po-Chun Chen, Chih-Hsin Tang, Liang-Wei Lin… in Journal of Hematology & Oncology (2017)

Article

DNA methylation evidence against the accelerated aging hypothesis of schizophrenia

The accelerated aging hypothesis of schizophrenia posits that physiological changes throughout the body that are associated with normal aging occur at an earlier age in individuals with schizophrenia. Testing ...

Brandon C. McKinney, Huang Lin, Ying Ding, David A. Lewis… in npj Schizophrenia (2017)

Article

Knee subchondral bone perfusion and its relationship to marrow fat and trabeculation on multi-parametric MRI and micro-CT in experimental CKD

The pathogenesis of chronic kidney disease (CKD) is multifactorial. In the progression of CKD arthropathy, arteriosclerosis may alter the knee subchondral bone marrow by altering blood flow through the bone va...

Chao-Ying Wang, Yu-Juei Hsu, Yi-Jen Peng, Herng-Sheng Lee… in Scientific Reports (2017)

Article

The relation between residual stress, interfacial structure and the joint property in the SiO_2f/SiO₂-Nb joints

In order to achieve a high-quality joint between SiO_2f/SiO₂ and metals, it is necessary to address the poor wettability of SiO_2f/SiO₂ and the high residual stress in SiO_2f/SiO₂-Nb joint. Here, we simultaneously r...

Qiang Ma, Zhuo Ran Li, Lai Shan Yang, **g Huang Lin, ** Ba… in Scientific Reports (2017)

Article

Anti-herpetic Medications and Reduced Risk of Dementia in Patients with Herpes Simplex Virus Infections—a Nationwide, Population-Based Cohort Study in Taiwan

This retrospective cohort study is to investigate the association between herpes simplex virus (HSV) infections and dementia, and the effects of anti-herpetic medications on the risk involved, using Taiwan’s N...

Nian-Sheng Tzeng, Chi-Hsiang Chung, Fu-Huang Lin, Chien-** Chiang… in Neurotherapeutics (2018)

Article

Long term impact of CTLA4 blockade immunotherapy on regulatory and effector immune responses in patients with melanoma

We previously reported early on-treatment significant modulation in circulating regulatory T cell (Treg), myeloid derived suppressor cells (MDSC) and antigen-specific type I CD4+ and CD8+ T cells that correlat...

Janet Retseck, Alexis Nasr, Yan Lin, Huang Lin… in Journal of Translational Medicine (2018)

Article

Neoadjuvant ipilimumab (3 mg/kg or 10 mg/kg) and high dose IFN-α2b in locally/regionally advanced melanoma: safety, efficacy and impact on T-cell repertoire

Neoadjuvant immunotherapy utilizing novel combinations has the potential to transform the standard of care for locally/regionally advanced melanoma. We hypothesized that neoadjuvant ipilimumab in combination w...

Ahmad Tarhini, Yan Lin, Huang Lin, Zahra Rahman… in Journal for ImmunoTherapy of Cancer (2018)

Article

Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer

Lung adenocarcinomas (LUADs) with mutations in the K-ras oncogene display dismal prognosis. Proinflammatory and immunomodulatory events that drive development of K-ras mutant LUAD are poorly understood. Here, we ...

Mauricio S. Caetano, Maya Hassane, Hieu T. Van, Emmanuel Bugarin… in Nature Communications (2018)