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Open AccessForce-induced Caspase-1-dependent pyroptosis regulates orthodontic tooth movement
Pyroptosis, an inflammatory caspase-dependent programmed cell death, plays a vital role in maintaining tissue homeostasis and activating inflammatory responses. Orthodontic tooth movement (OTM) is an aseptic f...
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Article
Open AccessSelf-promoted electroactive biomimetic mineralized scaffolds for bacteria-infected bone regeneration
Infected bone defects are a major challenge in orthopedic treatment. Native bone tissue possesses an endogenous electroactive interface that induces stem cell differentiation and inhibits bacterial adhesion an...
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Article
Open AccessClinical feasibility evaluation of a digital workflow of prosthetically oriented onlay bone grafting for horizontal alveolar augmentation: a prospective pilot study
Onlay bone grafting is considered highly reliable for reconstructing severe horizontal bone defects. A critical problem is how to achieve precise position of the bone block to control alveolar ridge dimensions...
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Article
Open AccessCraniofacial therapy: advanced local therapies from nano-engineered titanium implants to treat craniofacial conditions
Nano-engineering-based tissue regeneration and local therapeutic delivery strategies show significant potential to reduce the health and economic burden associated with craniofacial defects, including traumas ...
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Article
Transient Behaviors of Thermo-Hydraulic and Thermal Stratification in the Pressurizer Surgeline for the Nuclear Power Plant
In pressurized water reactor (PWR) system, the surgeline plays an important role in bonding the pressurizer and the primary circle. Some considerable problems, including the thermo-hydraulics, the thermal stra...
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Article
Characteristics of the transient thermal load and deformation of the evacuated receiver in solar parabolic trough collector
As a core element in solar parabolic trough collector, the evaluated receiver often runs under severe thermal conditions. Worse still, the transient thermal load is more likely to cause structural deformation ...
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Article
Open AccessMechanical load-induced H2S production by periodontal ligament stem cells activates M1 macrophages to promote bone remodeling and tooth movement via STAT1
Tooth movement is a unique bone remodeling process induced by mechanical stimulation. Macrophages are important in mediating inflammatory processes during mechanical load-induced tooth movement. However, how m...