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  1. Article

    Open Access

    Nanoparticle-mediated TRPV1 channel blockade amplifies cancer thermo-immunotherapy via heat shock factor 1 modulation

    The survival of malignant tumors is highly dependent on their intrinsic self-defense pathways such as heat shock protein (HSP) during cancer therapy. However, precisely dismantling self-defenses to amplify ant...

    Ting Li, Shuhui Jiang, Ying Zhang, Jie Luo, Ming Li, Hengte Ke in Nature Communications (2023)

  2. No Access

    Article

    Severe Postoperative Bleeding After Stapled Hemorrhoidopexy: Incidence and Causes

    Severe postoperative bleeding (SPB) represents a major issue of stapled hemorrhoidopexy (SH). The aim of the study is to assess SPB events over last 6 years. This essay is a retrospective study of clinical rec...

    Huabing Chen, Zaili Tang, Zhousong Wu, Renjie Shi in Indian Journal of Surgery (2021)

  3. No Access

    Article

    Precise nanomedicine for intelligent therapy of cancer

    Precise nanomedicine has been extensively explored for efficient cancer imaging and targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and clinical explorations. Here, we demonst...

    Huabing Chen, Zhanjun Gu, Hongwei An, Chunying Chen, Jie Chen in Science China Chemistry (2018)

  4. Article

    Open Access

    In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics

    The development of precision nanomedicines to direct nanostructure-based reagents into tumour-targeted areas remains a critical challenge in clinics. Chemical reaction-mediated localization in response to tumo...

    **angzhao Ai, Chris Jun Hui Ho, Junxin Aw in Nature Communications (2016)

  5. No Access

    Article

    Emulsifiers’ Composition Modulates Venous Irritation of the Nanoemulsions as a Lipophilic and Venous Irritant Drug Delivery System

    In this study, a nanoemulsion (NE) system was investigated for intravenous delivery of lipophilic and venous irritant drugs. NEs were prepared to deliver diallyl trisulfide (DT) for systemic therapy of bacteri...

    Chengwen Mao, Jiangling Wan, Huabing Chen, Huibi Xu, **angliang Yang in AAPS PharmSciTech (2009)

  6. No Access

    Article

    Preparation of PP-g-PA6 copolymers through reactive blending

    Dean Shi, Huabing Chen, R. K. Y. Li in Journal of Materials Science (2007)