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OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

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  1. Article

    Open Access

    A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair

    Inhibition of the Wnt antagonist sclerostin increases bone mass in patients with osteoporosis and in preclinical animal models. Here we show increased levels of the Wnt antagonist Dickkopf-1 (DKK-1) in animals...

    Monica Florio, Kannan Gunasekaran, Marina Stolina, **aodong Li in Nature Communications (2016)