9 Result(s)
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Article
Open AccessHuman metabolism and urinary excretion of seven neonicotinoids and neonicotinoid-like compounds after controlled oral dosages
Few human data on exposure and toxicity are available on neonicotinoids and neonicotinoid-like compounds (NNIs), an important group of insecticides worldwide. Specifically, exposure assessment of humans by bio...
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Toxicokinetics of N-ethyl-2-pyrrolidone and its metabolites in blood, urine and amniotic fluid of rats after oral administration
The toxicokinetics of N-ethyl-2-pyrrolidone (NEP), an embryotoxic organic solvent, has been studied in Sprague–Dawley rats after oral exposure. NEP and its metabolites 5-hydroxy-N-ethyl-2-pyrrolidone (5-HNEP) and...
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Article
Open AccessEnvironmentally prevalent polycyclic aromatic hydrocarbons can elicit co-carcinogenic properties in an in vitro murine lung epithelial cell model
Low molecular weight (LMW) polycyclic aromatic hydrocarbons (PAH) are the most abundant PAHs environmentally, occupationally, and are in cigarette smoke; however, little is known about their carcinogenic poten...
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Open AccessOxidatively damaged guanosine in white blood cells and in urine of welders: associations with exposure to welding fumes and body iron stores
The International Agency for Research on Cancer considers the carcinogenicity of welding fume of priority for re-evaluation. Genotoxic effects in experimental animals are still inconclusive. Here, we investiga...
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Partition of metals in the maternal/fetal unit and lead-associated decreases of fetal iron and manganese: an observational biomonitoring approach
To systematically study the partition of environmental metals including lead, mercury, and cadmium and essential minerals such as iron, manganese, copper, and zinc in the maternal/fetal unit of healthy pregnan...
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Internal exposure to carcinogenic polycyclic aromatic hydrocarbons and DNA damage: a null result in brief
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Assessment of micronuclei in lymphocytes from workers exposed to vapours and aerosols of bitumen
We investigated the micronucleus frequencies in peripheral blood lymphocytes of 225 mastic asphalt workers (age 17–62 years) and 69 non-bitumen-exposed road construction workers (age 18–64 years) in Germany be...
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DNA adducts and strand breaks in workers exposed to vapours and aerosols of bitumen: associations between exposure and effect
To study the associations between exposure to vapours and aerosols of bitumen and genotoxic effects, a cross-sectional and cross-shift study was conducted in 320 exposed workers and 118 non-exposed constructio...
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Article
Trends in the musk xylene concentrations in plasma samples from the general population from 1992/1993 to 1998 and the relevance of dermal uptake
Objectives: Musk xylene (MX), an environmentally important nitromusk compound, is used in different fragrances and soaps as substitute for natural musk. MX is known to occur in breast milk and plasma samples fro...
