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  1. Article

    Open Access

    Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome

    Genome sequences of the Chinese hamster and six Chinese hamster ovary cell lines provide a resource to aid in improving production of recombinant proteins.

    Nathan E Lewis, **n Liu, Yuxiang Li, Harish Nagarajan… in Nature Biotechnology (2013)

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  2. No Access

    Article

    Constraining the metabolic genotype–phenotype relationship using a phylogeny of in silico methods

  3. Our understanding of genotype–phenotype relationships has classically been qualitative, but recent advances are enabling us to overcome conceptual and technolo...

    4. Nathan E. Lewis, Harish Nagarajan, Bernhard O. Palsson in Nature Reviews Microbiology (2012)

  4. Article

    Open Access

    The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

    Since 1987, immortalized cells from the ovary of a Chinese hamster have been the workhorse for producing recombinant therapeutics, including monoclonal antibodies, blood factors, hormones, growth factors and e...

    Xun Xu, Harish Nagarajan, Nathan E Lewis, Shengkai Pan, Zhiming Cai… in Nature Biotechnology (2011)

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