16 Result(s)
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Article
Hannu Kiviranta
English
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Article
Open AccessPersistent organic pollutants in pregnant women potentially affect child development and thyroid hormone status
Potentially harmful effects of persistent organic pollutants (POPs) such as polychlorinated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT) on prenatal development and the endocrine system have been...
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Open AccessPrenatal exposures to mixtures of endocrine disrupting chemicals and children’s weight trajectory up to age 5.5 in the SELMA study
Exposure to endocrine disrupting chemicals (EDCs) may impact early growth, although information is limited on exposure to combination of multiple EDCs. We aimed to evaluate the effect of prenatal exposure to E...
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Open AccessPersistent organic pollutants, pre-pregnancy use of combined oral contraceptives, age, and time-to-pregnancy in the SELMA cohort
We are exposed to several chemicals such as persistent organic pollutants (POPs) in our everyday lives. Prior evidence has suggested that POPs may have adverse effects on reproductive function by disrupting ho...
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Open AccessIdentification of Sex-Specific Transcriptome Responses to Polychlorinated Biphenyls (PCBs)
PCBs are classified as xenoestrogens and carcinogens and their health risks may be sex-specific. To identify potential sex-specific responses to PCB-exposure we established gene expression profiles in a popula...
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Open AccessNo evidence of the role of early chemical exposure in the development of β-cell autoimmunity
Exposure to environmental chemicals can modulate the develo** immune system, but its role in the pathogenesis of type 1 diabetes is largely unexplored. Our objective was to study the levels of circulating co...
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Open AccessMicroRNA profile for health risk assessment: Environmental exposure to persistent organic pollutants strongly affects the human blood microRNA machinery
Persistent organic pollutants (POPs) are synthetic chemical substances that accumulate in our environment. POPs such as polychlorinated biphenyls (PCBs), hexachlorobenzene (HCB) and dichlorodiphenyltrichloroet...
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Open AccessPrediagnostic plasma concentrations of organochlorines and risk of B-cell non-Hodgkin lymphoma in envirogenomarkers: a nested case-control study
Evidence suggests a largely environmental component to non-Hodgkin’s lymphoma (NHL). Persistent organic pollutants (POPs) including polychlorinated biphenyls (PCBs), DDE and HCB have been repeatedly implicated...
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Open AccessCommon environmental chemicals do not explain atopy contrast in the Finnish and Russian Karelia
Atopic allergy is much more common in Finnish compared with Russian Karelia, although these areas are geographically and genetically close. To explore the role of environmental chemicals on the atopy differenc...
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Open AccessPersistent organic pollutants and non-alcoholic fatty liver disease in morbidly obese patients: a cohort study
In animal experiments persistent organic pollutants (POPs) cause hepatosteatosis. In epidemiological studies POPs have positive associations with serum markers of nonalcoholic fatty liver disease (NAFLD) and t...
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Open AccessAssociation between levels of persistent organic pollutants in adipose tissue and cryptorchidism in early childhood: a case–control study
Congenital cryptorchidism, i.e. failure of the testicular descent to the bottom of the scrotum, is a common birth defect. The evidence from epidemiological, wildlife, and animal studies suggests that exposure ...
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Cancer incidence in a cohort with high fish consumption
Evidence suggests that fish-derived omega-3 polyunsaturated fatty acids inhibit cancer promotion and progression. On the other hand, fish may contain endocrine-disrupting and potentially carcinogenic environme...
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Monitoring bisphenol A and estrogenic chemicals in thermal paper with yeast-based bioreporter assay
Bioluminescent Saccharomyces cerevisiae yeast-based bioreporters were used to monitor bisphenol A and other estrogenic chemicals in thermal paper samples collected mainly from Finland on two occasions in 2010/201...
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Open AccessAssociation of placenta organotin concentrations with growth and ponderal index in 110 newborn boys from Finland during the first 18 months of life: a cohort study
Humans are exposed to tributyltin (TBT), previously used as an antifouling paint in ships, mainly through fish consumption. As TBT is a known obesogen, we studied the association of placenta TBT and other orga...
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Open AccessPersistent organic pollutants in Finnish reindeer (Rangifer tarandus tarandus L.) and moose (Alces alces)
The aim of this study was to determine 17 Polychlorinated Dibenzo-p-dioxin and Dibenzofuran (PCDD/F) and 12 Dioxin-like Polychlorinated Biphenyl (DL-PCB) concentrations in the tissues of Finnish terrestrial herbi...
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A decision framework for possible remediation of contaminated sediments in the River Kymijoki, Finland
The paper describes the spatial contamination of the River Kymijoki, South-Eastern Finland, and the coastal region of the Gulf of Finland with PCDD/Fs and mercury. The findings of ecotoxicologial and human hea...
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Natal and Neonatal Teeth in Relation to Environmental Toxicants
Infants born to mothers heavily exposed to polychlorinated biphenyls (PCBs) and dibenzofurans (PCDFs) have earlier been reported to have increased prevalences of natal and neonatal teeth. Some tendency toward ...
