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Article
Open AccessReconstruction the feedback regulation of amino acid metabolism to develop a non-auxotrophic l-threonine producing Corynebacterium glutamicum
l-Threonine is an important feed additive with the third largest market size among the amino acids produced by microbial fermentation. The GRAS (generally regarded as safe) industrial workhorse Corynebacterium gl...
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Article
Open AccessKnowledge map** of UMOD of English published work from 1985 to 2022: a bibliometric analysis
UMOD is exclusively produced by renal epithelial cells. Recent genome-wide association studies (GWAS) suggested that common variants in UMOD gene are closely connected with the risk of CKD. However, a comprehe...
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Article
Open AccessComparison of two surgical interventions for lumbar brucella spondylitis in adults: a retrospective analysis
This retrospective study aimed to compare the clinical efficacy of the posterior procedure with the combined anterior and posterior procedure in the surgical management of lumbar Brucella spondylitis. From Jan...
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Article
Open AccessCRISPR-assisted rational flux-tuning and arrayed CRISPRi screening of an l-proline exporter for l-proline hyperproduction
Development of hyperproducing strains is important for biomanufacturing of biochemicals and biofuels but requires extensive efforts to engineer cellular metabolism and discover functional components. Herein, w...
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Article
Retraction Note to: Robust Model Selection and Estimation for Censored Survival Data with High Dimensional Genomic Covariates
The authors have retracted this article [1] because they found a fundamental mistake in the methodology that is not correctable at this time. This mistake is found in the methodology and the derivation of the ...
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Article
RETRACTED ARTICLE: Robust Model Selection and Estimation for Censored Survival Data with High Dimensional Genomic Covariates
When relating genomic data to survival outcomes, there are three main challenges that are the censored survival outcomes, the high-dimensionality of the genomic data, and the non-normality of data. We propose ...
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Article
Preparation of hollow silica microspheres with controlled shell thickness in supercritical fluids
This article presents a novel route to prepare hollow silica microspheres with well-defined wall thickness by using cross-linked polystyrene (PS) microspheres as templates with the assistance of supercritical ...
