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  1. Article

    Open Access

    Glomerular filtration rate measurement during platinum treatment for urothelial carcinoma: optimal methods for clinical practice

    We assessed the accuracy of four estimated glomerular filtration rate (eGFR) methods: MDRD, Cockcroft–Gault, CKD-EPI, and Wright.

    Dag Rune Stormoen, Ulla Nordström Joensen in International Journal of Clinical Oncology (2024)

  2. Article

    Open Access

    Outcomes of relapsed clinical stage I versus de novo metastatic testicular cancer patients: an analysis of the IGCCCG Update database

    Active surveillance after orchiectomy is the preferred management in clinical stage I (CSI) germ-cell tumours (GCT) associated with a 15 to 30% relapse rate.

    Jakob Lauritsen, Nicolas Sauvé, Alexey Tryakin, Di Maria Jiang in British Journal of Cancer (2023)

  3. No Access

    Article

    Testicular cancer

    Testicular cancer is the most common malignancy among men between 14 and 44 years of age, and its incidence has risen over the past two decades in Western countries. Both genetic and environmental factors cont...

    Liang Cheng, Peter Albers, Daniel M. Berney in Nature Reviews Disease Primers (2018)

  4. Article

    Open Access

    A randomized double-blind study of testosterone replacement therapy or placebo in testicular cancer survivors with mild Leydig cell insufficiency (Einstein-intervention)

    Elevated serum levels of luteinizing hormone and slightly decreased serum levels of testosterone (mild Leydig cell insufficiency) is a common hormonal disturbance in testicular cancer (TC) survivors. A number ...

    Mikkel Bandak, Niels Jørgensen, Anders Juul, Jakob Lauritsen in BMC Cancer (2017)

  5. Article

    Open Access

    Cancers of unknown primary origin (CUP) are characterized by chromosomal instability (CIN) compared to metastasis of know origin

    Cancers of unknown primary (CUPs) constitute ~5% of all cancers. The tumors have an aggressive biological and clinical behavior. The aim of the present study has been to uncover whether CUPs exhibit distinct m...

    Jonas Vikeså, Anne Kirstine H Møller, Bogumil Kaczkowski, Rehannah Borup in BMC Cancer (2015)

  6. No Access

    Article

    An open-label study to investigate the cardiac safety profile of cabazitaxel in patients with advanced solid tumors

    This study assessed the cardiovascular safety of cabazitaxel, based on thorough evaluation of QT and non-QT variables, and the relationship between pharmacokinetic and pharmacodynamic electrocardiographic (EC...

    Pierre Maison-Blanche, Shaker Dakhil, Ari Baron in Cancer Chemotherapy and Pharmacology (2014)

  7. Article

    Open Access

    Progressive Resistance Training and Cancer Testis (PROTRACT) - Efficacy of resistance training on muscle function, morphology and inflammatory profile in testicular cancer patients undergoing chemotherapy: design of a randomized controlled trial

    Standard treatment for patients with disseminated germ cell tumors is combination chemotherapy with bleomycin, etoposide and cisplatin (BEP). This treatment is highly effective, but the majority of patients ex...

    Jesper F Christensen, Jesper L Andersen, Lis Adamsen, Birgitte Lindegaard in BMC Cancer (2011)

  8. No Access

    Article

    Cisplatin nephrotoxicity

    Gedske Daugaard, Ulrik Abildgaard in Cancer Chemotherapy and Pharmacology (1989)

  9. No Access

    Article

    Effects of cisplatin on different measures of glomerular function in the human kidney with special emphasis on high-dose

    To investigate the effect of high-dose cisplatin (40 mg/m2 daily for 5 days), 51Cr-EDTA clearance was used as a measure of glomerular filtration rate (GFR). 51Cr-EDTA clearance decreased significantly from 109±3 ...

    Gedske Daugaard, Niels Rossing, Mikael Rørth in Cancer Chemotherapy and Pharmacology (1988)