16 Result(s)

Article

Allogeneic hematopoietic cell transplantation can overcome the adverse prognosis indicated by secondary-type mutations in de novo acute myeloid leukemia

Secondary-type mutations (STMs), namely SRSF2, SF3B1, U2AF1, ZRSR2, ASXL1, EZH2, BCOR, and STAG2, are more frequently detected in secondary acute myeloid leukemia (AML) than in de novo AML. Whether de novo AML wi...

Ga-Young Song, TaeHyung Kim, Seo-Yeon Ahn, Sung-Hoon Jung… in Bone Marrow Transplantation (2022)

Article

Expansion of cytotoxic natural killer cells in multiple myeloma patients using K562 cells expressing OX40 ligand and membrane-bound IL-18 and IL-21

Natural killer (NK) cell-based immunotherapy is a promising treatment approach for multiple myeloma (MM), but obtaining a sufficient number of activated NK cells remains challenging. Here, we report an improve...

Jaya Lakshmi Thangaraj, Minh-Trang Thi Phan… in Cancer Immunology, Immunotherapy (2022)

Article

Expanded natural killer cells augment the antimyeloma effect of daratumumab, bortezomib, and dexamethasone in a mouse model

The use of natural killer (NK) cells is a promising and safe immunotherapeutic approach in the field of cancer immunotherapy. However, combination treatments are required to enhance the effector functions and ...

Jaya Lakshmi Thangaraj, Seo-Yeon Ahn, Sung-Hoon Jung… in Cellular & Molecular Immunology (2021)

Article

A combination of immunoadjuvant nanocomplexes and dendritic cell vaccines in the presence of immune checkpoint blockade for effective cancer immunotherapy

Manh-Cuong Vo, Seo-Yeon Ahn, Tan-Huy Chu, Saji Uthaman… in Cellular & Molecular Immunology (2021)

Article

Prognostic impact of ¹⁸F-FDG PET/CT in patients with multiple myeloma presenting with renal impairment

Renal insufficiency (RI) is a frequent manifestation of multiple myeloma (MM) at time of diagnosis but there is no reliable prognostic factor for patients with MM presenting with RI. This study investigated th...

Seo-Yeon Ahn, Hwa Kyung Park, Joon Ho Moon… in International Journal of Hematology (2021)

Article

Allogeneic transplant can abrogate the risk of relapse in the patients of first remission acute myeloid leukemia with detectable measurable residual disease by next-generation sequencing

In patients with acute myeloid leukemia (AML) consolidation treatment options are between allogeneic hematopoietic stem cell transplantation (HCT) and chemotherapy, based on disease risk at the time of initial...

Jae-Sook Ahn, TaeHyung Kim, Sung-Hoon Jung, Seo-Yeon Ahn… in Bone Marrow Transplantation (2021)

Article

Water-soluble paclitaxel by conjugation to hyperbranched polyglycidols

Chemical conjugates composed of paclitaxel (PTXL) and hyperbranched polyglycidols (HBP) were synthesized using glutaric anhydride as a “bridge” with esterification in dimethylformamide. A series of HBP–PTXL co...

**nhua Huang, Ga Young Song, Seong Jae Yu, Il Kim in Journal of Materials Science (2013)

Article

(E)-N-((1H-benzo[d]imidazol-2-yl)(phenyl)-methylene)quinolin-8-amino cobalt(II), iron(II), nickel(II), chromium(III), and vanadium(III) complexes and their activities towards ethylene and 1,3-butadiene

Hyuk Chul Chang, Bong Cheol Son, Ga Young Song, ** Young Shin… in Macromolecular Research (2013)