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Article

AKT1-CREB stimulation of PDGFRα expression is pivotal for PTEN deficient tumor development

As evidenced by the behavior of loss-of-function mutants of PTEN in the context of a gain-of-function mutation of AKT1, the PTEN-AKT1 signaling pathway plays a critical role in human cancers. In this study, we...

**aofeng Wan, Meng Zhou, Fuqiang Huang, Na Zhao, Xu Chen, Yuncui Wu… in Cell Death & Disease (2021)