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  1. Article

    Open Access

    Treatment Persistence and Switching Patterns of Adalimumab Biosimilar ABP 501 in European Patients with Rheumatologic Diseases

    ABP 501 was an adalimumab (ADA) biosimilar approved for treating immune-mediated inflammatory diseases (IMIDs) including rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS). I...

    Ran **, Silvia Kruppert, Florian Scholz, Isabelle Bardoulat in Rheumatology and Therapy (2024)

  2. Article

    Open Access

    Coastal El Niño triggers rapid marine silicate alteration on the seafloor

    Marine silicate alteration plays a key role in the global carbon and cation cycles, although the timeframe of this process in response to extreme weather events is poorly understood. Here we investigate surfac...

    Sonja Geilert, Daniel A. Frick, Dieter Garbe-Schönberg in Nature Communications (2023)

  3. Article

    Open Access

    Biogeochemical feedbacks may amplify ongoing and future ocean deoxygenation: a case study from the Peruvian oxygen minimum zone

    A new box model is employed to simulate the oxygen-dependent cycling of nutrients in the Peruvian oxygen minimum zone (OMZ). Model results and data for the present state of the OMZ indicate that dissolved iron...

    Klaus Wallmann, Yonss S. José, Mark J. Hopwood, Christopher J. Somes in Biogeochemistry (2022)

  4. Article

    Open Access

    Interactions between temperature and energy supply drive microbial communities in hydrothermal sediment

    Temperature and bioavailable energy control the distribution of life on Earth, and interact with each other due to the dependency of biological energy requirements on temperature. Here we analyze how temperatu...

    Lorenzo Lagostina, Søs Frandsen, Barbara J. MacGregor in Communications Biology (2021)

  5. Article

    Open Access

    MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer

    Metastasis Associated in Colon Cancer 1 (MACC1) is a novel prognostic, predictive and causal biomarker for tumor progression and metastasis in many cancer types, including colorectal cancer. Besides its clinic...

    Francesca Imbastari, Mathias Dahlmann in Cellular and Molecular Life Sciences (2021)

  6. No Access

    Article

    Periodic changes in the Cretaceous ocean and climate caused by marine redox see-saw

    Periodic changes in sediment composition are usually ascribed to insolation forcing controlled by Earth’s orbital parameters. During the Cretaceous Thermal Maximum at 97–91 Myr ago (Ma), a 37–50-kyr-long cycle...

    Klaus Wallmann, Sascha Flögel, Florian Scholz, Andrew W. Dale in Nature Geoscience (2019)

  7. No Access

    Article

    Benthic nematode biodiversity of the Abzu, Tiamat and Michael Ivanov mud volcanoes located along the SWIM fracture zone (Gulf of Cadiz)

    Studies that focus on meiofaunal assemblages of deep-sea mud volcanoes show an unpredictable abundance and diversity in a clear response to the different environmental conditions of the seeped sediment. The mu...

    Sofia P. Ramalho, Carlos Ribeiro, Christian Hensen, Florian Scholz in Marine Biodiversity (2018)

  8. No Access

    Article

    Dendritic cell-mediated survival signals in Eμ-Myc B-cell lymphoma depend on the transcription factor C/EBPβ

    The capacity of dendritic cells (DCs) to regulate tumour-specific adaptive immune responses depends on their proper differentiation and homing status. Whereas DC-associated tumour-promoting functions are linke...

    Armin Rehm, Marcel Gätjen, Kerstin Gerlach, Florian Scholz in Nature Communications (2014)

  9. No Access

    Article

    The impact of ocean deoxygenation on iron release from continental margin sediments

    Bioavailable iron is released from anoxic sediments, such as those that underlie the Peruvian upwelling zone. Analyses of iron levels in sediments from this region suggest that iron release occurs in a relativ...

    Florian Scholz, James McManus, Alan C. Mix, Christian Hensen in Nature Geoscience (2014)

  10. No Access

    Article

    Active mud volcanoes on the upper slope of the western Nile deep-sea fan—first results from the P362/2 cruise of R/V Poseidon

    In February 2008, cruise P362/2 was undertaken aboard R/V Poseidon to the Giza and North Alex mud volcanoes (MVs) on the upper slope of the western Nile deep-sea fan. Emitted fluids were strongly depleted in chlo...

    Tomas Feseker, Kevin R. Brown, Cecile Blanchet, Florian Scholz in Geo-Marine Letters (2010)

  11. No Access

    Article

    LerM – Lehrsystem für Kontrapunkt-Kompositionen im Stile Palestrinas

    Der Palestrina-Kontrapunkt nimmt in der Musiktheorie-Ausbildung eine wichtige Stellung ein.

    Mirco Kuhlmann, Florian Scholz, Marcus Barann, Paul Grathwohl in Informatik-Spektrum (2005)

  12. No Access

    Article

    Viability and sunlight sensitivity of oak pollen and its implications for pollen-mediated gene flow

    Pollen-mediated gene flow and the male reproductive success of wind-pollinated trees depend on the initial viability of the pollen and the changes that occur in its viability during transport in the atmosphere...

    Silvio Schueler, Katharina Heinke Schlünzen, Florian Scholz in Trees (2005)

  13. No Access

    Article

    Einfluß eines erhöhten CO2-Gehaltes in der Luft auf Wachstumsparameter verschiedener Rotbuchen-Provenienzen (Fagus sylvatica L.) bei unterschiedlichem Lichtgenuß

    Die Reaktion von sieben Provenienzen aus dem Verbreitungsgebiet der Rotbuche (Fagus sylvatica L.) auf erhöhte atmosphärische CO2-Konzentrationen bei unterschiedlichem Lichtangebot wurde in einem Gewächshausversuc...

    Wolf-Ulrich Kriebitzsch, Mirko Liesebach in Forstwissenschaftliches Centralblatt verei… (1999)

  14. No Access

    Article

    Growth and protection against oxidative stress in young clones and mature spruce trees (Picea abies L.) at high altitudes

    Clones of Norway spruce (Picea abies L.) were grown for several years on an altitudinal gradient (1750 m, 1150 m and 800 m above sea level) to study the effects of environmental × genetic interactions on growth ...

    Andrea Polle, Lars O. Baumbusch, Christa Oschinski, Monika Eiblmeier in Oecologia (1999)

  15. No Access

    Article

    Contribution of temperate forests to the world's carbon budget

    Temperate forests currently cover about 600 MHa, about half of their potential. Almost all these forests have been directly impacted by humans. The total living biomass in trees (including roots) was estimated...

    Linda S. Heath, Pekka E. Kauppi, Peter Burschel in Water, Air, and Soil Pollution (1993)

  16. No Access

    Article

    Über den Torus der Hoftüpfel in Coniferenholz

    Walter Liese, Josef Bauch, Florian Scholz in Naturwissenschaften (1967)