4 Result(s)
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Article
Fengming Zhu
English
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Article
Open AccessBlocking connexin 43 and its promotion of ATP release from renal tubular epithelial cells ameliorates renal fibrosis
Whether metabolites derived from injured renal tubular epithelial cells (TECs) participate in renal fibrosis is poorly explored. After TEC injury, various metabolites are released and among the most potent is ...
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Article
Protective Effects of PGC-1α on the Blood Brain Barrier After Acute Kidney Injury
Blood brain barrier (BBB) disruption plays an important role in brain injury after acute kidney injury (AKI). However, its underlying mechanisms remain poorly understood. Recent evidence has revealed that prop...
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Article
Open AccessPutative endothelial progenitor cells do not promote vascular repair but attenuate pericyte–myofibroblast transition in UUO-induced renal fibrosis
Putative endothelial progenitor cells (pEPCs) have been confirmed to participate in alleviation of renal fibrosis in several ischaemic diseases. However, their mechanistic effect on renal fibrosis, which is ch...
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Open AccessPretreatment of Huaiqihuang extractum protects against cisplatin-induced nephrotoxicity
Cisplatin is a commonly used chemotherapeutic agent in the treatment of different types of malignant tumors, but nephrotoxicity limits its usage. Therefore, in this study, we aimed to determine the possible pr...
